The toxicity of amyloid‐forming proteins is correlated with their interactions with cell
membranes. Binding events between amyloidogenic proteins and membranes result in …

Protein misfolding and metal ion dyshomeostasis are believed to underlie numerous
neurodegenerative diseases, including Alzheimer's disease (AD). The pathological hallmark …

Context Blood-based analytes may be indicators of pathological processes in Alzheimer
disease (AD). Objective To identify plasma proteins associated with AD pathology using a …

The common underlying feature of most neurodegenerative diseases such as Alzheimer
disease (AD), prion diseases, Parkinson disease (PD), and amyotrophic lateral sclerosis …

This tutorial review presents descriptions of two amyloidogenic proteins, amyloid-β (Aβ)
peptides and islet amyloid polypeptide (IAPP), whose misfolding propensities are implicated …

Clusterin, also known as apolipoprotein J, is a versatile chaperone molecule which contains
several amphipathic and coiled-coil α-helices, typical characteristics of small heat shock …

The amyloidoses are a group of protein misfolding diseases in which the precursor protein
undergoes a conformational change that triggers the formation of amyloid fibrils in different …

Amyloid fibrils are self‐assembled fibrous protein aggregates that are associated with a
number of presently incurable diseases such as Alzheimer's and Parkinson's disease …

Deposition of amyloid plaques in the brains of Alzheimer's disease (AD) patients is a
hallmark of the disease. AD plaques consist primarily of the beta-amyloid (Aβ) peptide but …

The brain is the most lipid-rich organ in the body and, owing to the impermeable nature of
the blood–brain barrier, lipid and lipoprotein metabolism within this organ is distinct from the …