Leading the pack: Best practices in comparative canine cancer genomics to inform human oncology
CA London, H Gardner, S Zhao… - Veterinary and …, 2023 - Wiley Online Library
Pet dogs develop spontaneous cancers at a rate estimated to be five times higher than that
of humans, providing a unique opportunity to study disease biology and evaluate novel …
of humans, providing a unique opportunity to study disease biology and evaluate novel …
Biologically meaningful genome interpretation models to address data underdetermination for the leaf and seed ionome prediction in Arabidopsis thaliana
Genome interpretation (GI) encompasses the computational attempts to model the
relationship between genotype and phenotype with the goal of understanding how the first …
relationship between genotype and phenotype with the goal of understanding how the first …
Genomic and transcriptomic characterization of canine osteosarcoma cell lines: a valuable resource in translational medicine
C Gola, D Giannuzzi, A Rinaldi, S Iussich… - Frontiers in veterinary …, 2021 - frontiersin.org
Osteosarcoma (OSA) represents the most common primary bone tumor in dogs and is
characterized by a highly aggressive behavior. Cell lines represent one of the most suitable …
characterized by a highly aggressive behavior. Cell lines represent one of the most suitable …
[HTML][HTML] Mutational Landscape of KIT Proto-Oncogene Coding Sequence in 62 Canine Cutaneous and Subcutaneous Mast Cell Tumors
L Montanucci, E Guidolin, RM Lopparelli… - Veterinary …, 2024 - mdpi.com
Canine mast cell tumors (MCTs) are common skin neoplasms with varying biological
behaviors. The KIT proto-oncogene plays a key role in the development of these tumors, and …
behaviors. The KIT proto-oncogene plays a key role in the development of these tumors, and …
The transverse ultrasonogram of thyroid papillary carcinoma has a better prediction accuracy than the longitudinal one
B Yu, Z Wang, R Zhu, X Feng, M Qi, J Li, R Zhao… - IEEE …, 2019 - ieeexplore.ieee.org
Thyroid produces multiple essential hormones for vital life processes. Thyroid cancer has no
symptoms and may be detected by ultrasound imaging incidentally for other medical …
symptoms and may be detected by ultrasound imaging incidentally for other medical …
Using machine learning to predict pathogenicity of genomic variants throughout the human genome
P Rentzsch - 2023 - edoc.hu-berlin.de
More than 6,000 diseases are estimated to be caused by genomic variants. This can happen
in many possible ways: a variant may stop the translation of a protein, interfere with gene …
in many possible ways: a variant may stop the translation of a protein, interfere with gene …
[HTML][HTML] Incorporating structural features to improve the prediction and understanding of pathogenic amino acid substitutions
Background: The wide application of gene sequencing has accumulated numerous amino
acid substitutions (AAS) with unknown significance, posing significant challenges to …
acid substitutions (AAS) with unknown significance, posing significant challenges to …
Resolving the major dyslipidemia phenotypes and genetic risk factors for familial hyperlipidemia in Miniature Schnauzers
NM Tate - 2022 - search.proquest.com
Hyperlipidemia is common in the Miniature Schnauzer breed, especially those over the age
of 10. Hyperlipidemia is defined as an increased concentration of lipids (ie, triglycerides …
of 10. Hyperlipidemia is defined as an increased concentration of lipids (ie, triglycerides …
ПОЛИМОРФИЗМ ДНК СОБАК (CANIS FAMILIARIS L.). V. ОДНОНУКЛЕОТИДНЫЕ ЗАМЕНЫ В ЯДЕРНОМ ГЕНОМЕ
РР ГАРАФУТДИНОВ, ДА ЧЕМЕРИС… - 2021 - elibrary.ru
Кратко рассмотрены особенности ядерного генома собак, включая ряд референсных
геномов, уделив наибольшее внимание однонуклеотидному полиморфизму ДНК (ОНП) …
геномов, уделив наибольшее внимание однонуклеотидному полиморфизму ДНК (ОНП) …