Disclosing results of tests for covert consciousness: A framework for ethical translation

MJ Young, K Kazazian, D Fischer, IA Lissak… - Neurocritical Care, 2024 - Springer
The advent of neurotechnologies including advanced functional magnetic resonance
imaging and electroencephalography to detect states of awareness not detectable by …

Proceedings of the first pediatric coma and disorders of consciousness symposium by the curing coma campaign, pediatric neurocritical care research group, and …

VL Boerwinkle, NF Schor, BS Slomine, E Molteni… - Neurocritical care, 2023 - Springer
This proceedings article presents the scope of pediatric coma and disorders of
consciousness based on presentations and discussions at the First Pediatric Disorders of …

Common data elements for disorders of consciousness: Recommendations from the working group on neuroimaging

BL Edlow, VL Boerwinkle, J Annen, M Boly… - Neurocritical care, 2023 - Springer
Background Over the past 5 decades, advances in neuroimaging have yielded insights into
the pathophysiologic mechanisms that cause disorders of consciousness (DoC) in patients …

[HTML][HTML] Association of network connectivity via resting state functional MRI with consciousness, mortality, and outcomes in neonatal acute brain injury

VL Boerwinkle, BL Sussman, I Manjón, L Mirea… - NeuroImage: Clinical, 2022 - Elsevier
Background An accurate and comprehensive test of integrated brain network function is
needed for neonates during the acute brain injury period to inform on morbidity. This …

Treatable brain network biomarkers in children in coma using task and resting-state functional MRI: a case series

VL Boerwinkle, BL Sussman, J Broman-Fulks… - Frontiers in …, 2023 - frontiersin.org
The withdrawal of life-sustaining therapies is frequently considered for pediatric patients with
severe acute brain injuries who are admitted to the intensive care unit. However, it is worth …

Revisiting the standard for modeling functional brain network activity: Application to consciousness

A Grigis, C Gomez, V Frouin, E Duchesnay, L Uhrig… - PloS one, 2024 - journals.plos.org
Functional connectivity (FC) of resting-state fMRI time series can be estimated using
methods that differ in their temporal sensitivity (static vs. dynamic) and the number of regions …

Covert Consciousness in the ICU

BL Edlow, DK Menon - Critical Care Medicine, 2024 - journals.lww.com
OBJECTIVES: For critically ill patients with acute severe brain injuries, consciousness may
reemerge before behavioral responsiveness. The phenomenon of covert consciousness (ie …

Functional MRI for acute covert consciousness: Emerging data and implementation case series

VL Boerwinkle, K Gillette, CA Rubinos… - Seminars in …, 2023 - thieme-connect.com
Although research studies have begun to demonstrate relationships between disorders of
consciousness and brain network biomarkers, there are limited data on the practical aspects …

A protocol for a multicenter randomized and personalized controlled trial using rTMS in patients with disorders of consciousness

MM Vitello, MJ Rosenfelder, P Cardone, M Niimi… - Frontiers in …, 2023 - frontiersin.org
Background Improving the functional recovery of patients with DoC remains one of the
greatest challenges of the field. Different theories exist about the role of the anterior …

Resting-state functional magnetic resonance imaging network association with mortality, epilepsy, cognition, and motor two-year outcomes in suspected severe …

VL Boerwinkle, I Manjón, BL Sussman, A McGary… - Pediatric Neurology, 2024 - Elsevier
Abstract Background and Objectives In acute brain injury of neonates, resting-state
functional magnetic resonance imaging (MRI)(RS) showed incremental association with …