BACKGROUND Since the 1998 European Respiratory Society (ERS) lower respiratory tract
infection (LRTI) guidelines [1] were published, the evidence on which they were based has …

Chronic obstructive pulmonary disease (COPD) is the fourth leading cause of death in the
United States. The precise role of bacterial infection in the course and pathogenesis of …

Evidence supporting that gut problems are linked to ASD symptoms has been accumulating
both in humans and animal models of ASD. Gut microbes and their metabolites may be …

Whole metagenome analysis has the potential to reveal functional triggers of skin diseases,
but issues of cost, robustness and sampling efficacy have limited its application. Here, we …

The purpose of this study was to determine the bacterial diversity in the human subgingival
plaque by using culture-independent molecular methods as part of an ongoing effort to …

The microbiome plays many roles in human health, often through the exclusive lens of
clinical interest. The inevitable end point for all living hosts, death, has its own altered …

Exacerbations of COPD are thought to be caused by interactions between host factors,
bacteria, viruses, and changes in air quality to produce increased inflammation in the lower …

There is a growing appreciation for the role of the gut microbiome in human health and
disease. Aided by advances in sequencing technologies and analytical methods, recent …

Haemophilus parainfluenzae is a Gram-negative opportunist pathogen within the mucus of
the nose and mouth without significant symptoms and has an ability to cause various …

Despite the high worldwide prevalence of gallstone disease, the role of the biliary microbiota
in gallstone pathogenesis remains obscure. Next-generation sequencing offers advantages …