OCT angiography and its retinal biomarkers

TT Hormel, Y Jia - Biomedical Optics Express, 2023 - opg.optica.org
Optical coherence tomography angiography (OCTA) is a high-resolution, depth-resolved
imaging modality with important applications in ophthalmic practice. An extension of …

Advances in structural and functional retinal imaging and biomarkers for early detection of diabetic retinopathy

Z Zhang, C Deng, YM Paulus - Biomedicines, 2024 - mdpi.com
Diabetic retinopathy (DR), a vision-threatening microvascular complication of diabetes
mellitus (DM), is a leading cause of blindness worldwide that requires early detection and …

Surgical microscope integrated MHz SS-OCT with live volumetric visualization

A Britten, P Matten, J Weiss… - Biomedical Optics …, 2023 - opg.optica.org
Intraoperative optical coherence tomography is still not overly pervasive in routine
ophthalmic surgery, despite evident clinical benefits. That is because today's spectral …

[HTML][HTML] DISCOVER: 2-d multiview summarization of optical coherence tomography angiography for automatic diabetic retinopathy diagnosis

MEH Daho, Y Li, R Zeghlache, H Le Boité… - Artificial Intelligence in …, 2024 - Elsevier
Diabetic Retinopathy (DR), an ocular complication of diabetes, is a leading cause of
blindness worldwide. Traditionally, DR is monitored using Color Fundus Photography (CFP) …

Applications of optical coherence tomography angiography in glaucoma: current status and future directions

R Shen, LKY Chan, ACW Yip, PP Chan - Frontiers in Medicine, 2024 - frontiersin.org
Glaucoma is a leading cause of irreversible blindness worldwide, with its pathophysiology
remaining inadequately understood. Among the various proposed theories, the vascular …

[HTML][HTML] Association of diabetic lesions and retinal nonperfusion using widefield multimodal imaging

H Stino, KL Huber, M Niederleithner, N Mahnert… - Ophthalmology …, 2023 - Elsevier
Purpose To evaluate the association of microvascular lesions on ultrawidefield (UWF) color
fundus (CF) images with retinal nonperfusion (RNP) up to the midperiphery on single …

Single-shot OCT and OCT angiography for slab-specific detection of diabetic retinopathy

GB Liang, TT Hormel, X Wei, Y Guo, J Wang… - Biomedical Optics …, 2023 - opg.optica.org
In this study, we present an optical coherence tomographic angiography (OCTA) prototype
using a 500 kHz high-speed swept-source laser. This system can generate a 75-degree field …

Evaluating deep learning techniques for identifying tongue features in subthreshold depression: a prospective observational study

B Han, Y Chang, R Tan, C Han - Frontiers in Psychiatry, 2024 - frontiersin.org
Objective This study aims to evaluate the potential of using tongue image features as non-
invasive biomarkers for diagnosing subthreshold depression and to assess the correlation …

Multiple instance learning based classification of diabetic retinopathy in weakly-labeled widefield OCTA en face images

P Matten, J Scherer, T Schlegl, J Nienhaus, H Stino… - Scientific Reports, 2023 - nature.com
Diabetic retinopathy (DR), a pathologic change of the human retinal vasculature, is the
leading cause of blindness in working-age adults with diabetes mellitus. Optical coherence …

Context-aware real-time semantic view expansion of intraoperative 4D OCT

M Sommersperger, P Matten, T Wang… - … on Medical Imaging, 2025 - ieeexplore.ieee.org
Four-dimensional microscope-integrated optical coherence tomography enables volumetric
imaging of tissue structures and tool-tissue interactions in ophthalmic surgery at interactive …