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Sleep and anxiety: From mechanisms to interventions
Anxiety is the most common mental health problem worldwide. Epidemiological studies
show that sleep disturbances, particularly insomnia, affect∼ 50% of individuals with anxiety …
show that sleep disturbances, particularly insomnia, affect∼ 50% of individuals with anxiety …
Insomnia disorder: State of the science and challenges for the future
Insomnia disorder comprises symptoms during night and day that strongly affect quality of
life and wellbeing. Prolonged sleep latency, difficulties to maintain sleep and early morning …
life and wellbeing. Prolonged sleep latency, difficulties to maintain sleep and early morning …
[HTML][HTML] Brain mechanisms of insomnia: new perspectives on causes and consequences
While insomnia is the second most common mental disorder, progress in our understanding
of underlying neurobiological mechanisms has been limited. The present review addresses …
of underlying neurobiological mechanisms has been limited. The present review addresses …
Hyperarousal in insomnia disorder: Current evidence and potential mechanisms
Insomnia disorder is among the most frequent mental disorders, making research on its
aetiology and pathophysiology particularly important. A unifying element of many …
aetiology and pathophysiology particularly important. A unifying element of many …
Overnight neuronal plasticity and adaptation to emotional distress
Expressions such as 'sleep on it'refer to the resolution of distressing experiences across a
night of sound sleep. Sleep is an active state during which the brain reorganizes the …
night of sound sleep. Sleep is an active state during which the brain reorganizes the …
Restless REM sleep impedes overnight amygdala adaptation
Animal studies show that insufficient silencing of the locus coeruleus (LC) during REM sleep
impairs sleep-related brain plasticity. Restless REM sleep, a characteristic of several …
impairs sleep-related brain plasticity. Restless REM sleep, a characteristic of several …
[HTML][HTML] Adolescent sleep and the foundations of prefrontal cortical development and dysfunction
Modern life poses many threats to good-quality sleep, challenging brain health across the
lifespan. Curtailed or fragmented sleep may be particularly damaging during adolescence …
lifespan. Curtailed or fragmented sleep may be particularly damaging during adolescence …
Affect and arousal in insomnia: through a lens of neuroimaging studies
Abstract Purpose of Review Previous research has struggled with identifying clear-cut,
objective counterparts to subjective distress in insomnia. Approaching this discrepancy with …
objective counterparts to subjective distress in insomnia. Approaching this discrepancy with …
Altered thalamic connectivity in insomnia disorder during wakefulness and sleep
Insomnia disorder is the most common sleep disorder and has drawn increasing attention.
Many studies have shown that hyperarousal plays a key role in the pathophysiology of …
Many studies have shown that hyperarousal plays a key role in the pathophysiology of …
Increased connectivity of the anterior cingulate cortex is associated with the tendency to awakening during N2 sleep in patients with insomnia disorder
Y Guo, G Zou, Y Shao, J Chen, Y Li, J Liu, P Yao… - Sleep, 2023 - academic.oup.com
Abstract Study Objectives To investigate the relationship between sleep transition dynamics
and stage-specific functional connectivity (FC) of the anterior cingulate cortex (ACC) in …
and stage-specific functional connectivity (FC) of the anterior cingulate cortex (ACC) in …