Blood-brain barrier: from physiology to disease and back
The blood-brain barrier (BBB) prevents neurotoxic plasma components, blood cells, and
pathogens from entering the brain. At the same time, the BBB regulates transport of …
pathogens from entering the brain. At the same time, the BBB regulates transport of …
Blood–brain barrier breakdown in Alzheimer disease and other neurodegenerative disorders
MD Sweeney, AP Sagare, BV Zlokovic - Nature Reviews Neurology, 2018 - nature.com
The blood–brain barrier (BBB) is a continuous endothelial membrane within brain
microvessels that has sealed cell-to-cell contacts and is sheathed by mural vascular cells …
microvessels that has sealed cell-to-cell contacts and is sheathed by mural vascular cells …
Advancing research diagnostic criteria for Alzheimer's disease: the IWG-2 criteria
In the past 8 years, both the International Working Group (IWG) and the US National Institute
on Aging–Alzheimer's Association have contributed criteria for the diagnosis of Alzheimer's …
on Aging–Alzheimer's Association have contributed criteria for the diagnosis of Alzheimer's …
The role of brain vasculature in neurodegenerative disorders
Adequate supply of blood and structural and functional integrity of blood vessels are key to
normal brain functioning. On the other hand, cerebral blood flow shortfalls and blood–brain …
normal brain functioning. On the other hand, cerebral blood flow shortfalls and blood–brain …
Vascular dysfunction—the disregarded partner of Alzheimer's disease
Increasing evidence recognizes Alzheimer's disease (AD) as a multifactorial and
heterogeneous disease with multiple contributors to its pathophysiology, including vascular …
heterogeneous disease with multiple contributors to its pathophysiology, including vascular …
A Deep Learning Model to Predict a Diagnosis of Alzheimer Disease by Using 18F-FDG PET of the Brain
Purpose To develop and validate a deep learning algorithm that predicts the final diagnosis
of Alzheimer disease (AD), mild cognitive impairment, or neither at fluorine 18 (18F) …
of Alzheimer disease (AD), mild cognitive impairment, or neither at fluorine 18 (18F) …
Plasma phospholipids identify antecedent memory impairment in older adults
Alzheimer's disease causes a progressive dementia that currently affects over 35 million
individuals worldwide and is expected to affect 115 million by 2050 (ref. 1). There are no …
individuals worldwide and is expected to affect 115 million by 2050 (ref. 1). There are no …
EANM procedure guidelines for brain PET imaging using [18F]FDG, version 3
The present procedural guidelines summarize the current views of the EANM Neuro-
Imaging Committee (NIC). The purpose of these guidelines is to assist nuclear medicine …
Imaging Committee (NIC). The purpose of these guidelines is to assist nuclear medicine …
A review on neuroimaging-based classification studies and associated feature extraction methods for Alzheimer's disease and its prodromal stages
Neuroimaging has made it possible to measure pathological brain changes associated with
Alzheimer's disease (AD) in vivo. Over the past decade, these measures have been …
Alzheimer's disease (AD) in vivo. Over the past decade, these measures have been …
[HTML][HTML] The blood-brain barrier in Alzheimer's disease
E Zenaro, G Piacentino, G Constantin - Neurobiology of disease, 2017 - Elsevier
Alzheimer's disease (AD) is a chronic neurodegenerative disorder characterized by the
pathological accumulation of amyloid beta (Aβ) peptides and neurofibrillary tangles …
pathological accumulation of amyloid beta (Aβ) peptides and neurofibrillary tangles …