Peptides, new tools for plant protection in eco-agriculture

YM Zhang, DX Ye, Y Liu, XY Zhang, YL Zhou… - Advanced …, 2023 - Elsevier
As important physiological regulators, peptides have been used in many fields including
medicine, cosmetics, healthcare products, animal nutrition and health, and plant nutrition …

Progress and challenges in the field of snakebite envenoming therapeutics

JM Gutiérrez, N R. Casewell… - Annual Review of …, 2024 - annualreviews.org
Snakebite envenoming kills and maims hundreds of thousands of people every year,
especially in the rural settings of tropical regions. Envenomings are still treated with animal …

De novo designed proteins neutralize lethal snake venom toxins

S Vázquez Torres, M Benard Valle, SP Mackessy… - Nature, 2025 - nature.com
Snakebite envenoming remains a devastating and neglected tropical disease, claiming over
100,000 lives annually and causing severe complications and long-lasting disabilities for …

[HTML][HTML] Towards better antivenoms: navigating the road to new types of snakebite envenoming therapies

S Thumtecho, NJ Burlet, A Ljungars… - Journal of Venomous …, 2023 - SciELO Brasil
Snakebite envenoming is a significant global health challenge, and for over a century,
traditional plasma-derived antivenoms from hyperimmunized animals have been the primary …

Venom biotechnology: casting light on nature's deadliest weapons using synthetic biology

T Lüddecke, A Paas, RJ Harris, L Talmann… - … in bioengineering and …, 2023 - frontiersin.org
Venoms are complex chemical arsenals that have evolved independently many times in the
animal kingdom. Venoms have attracted the interest of researchers because they are an …

Heterologous expression and function of cholesterol oxidase: A review

H Cui, MH Shahrajabian, Y Kuang… - Protein and Peptide …, 2023 - ingentaconnect.com
Cholesterol was first found in gallstones as an animal sterol; hence it is called cholesterol.
Cholesterol oxidase is the chief enzyme in the process of cholesterol degradation. Its role is …

A previously unrecognized superfamily of macro-conotoxins includes an inhibitor of the sensory neuron calcium channel Cav2. 3

CM Hackney, P Flórez Salcedo, E Mueller, TL Koch… - Plos …, 2023 - journals.plos.org
Animal venom peptides represent valuable compounds for biomedical exploration. The
venoms of marine cone snails constitute a particularly rich source of peptide toxins, known …

Determining the pharmacological potential and biological role of linear pseudoscorpion toxins via functional profiling

P Erkoc, S Schiffmann, T Ulshöfer, M Henke, M Marner… - Iscience, 2024 - cell.com
Arthropod venoms contain bioactive molecules attractive for biomedical applications.
However, few of these have been isolated, and only a tiny number has been characterized …

[HTML][HTML] A single-chain variable fragment selected against a conformational epitope of a recombinantly produced snake toxin using phage display

C Rimbault, PD Knudsen, A Damsbo, K Boddum… - New …, 2023 - Elsevier
Phage display technology is a powerful tool for selecting monoclonal antibodies against a
diverse set of antigens. Within toxinology, however, it remains challenging to generate …

[HTML][HTML] Exploring the Diversity and Function of Serine Proteases in Toxicofera Reptile Venoms: A Comprehensive Overview

JFD Vidal, MF Schwartz, AV Garay, NF Valadares… - Toxins, 2024 - mdpi.com
Toxicofera reptile venoms are composed of several toxins, including serine proteases.
These proteases are glycosylated enzymes that affect the prey's hemostatic system. Their …