HIV-associated tuberculosis

G Meintjes, G Maartens - New England Journal of Medicine, 2024 - Mass Medical Soc
Key Points HIV-Associated Tuberculosis Almost half of inpatients with human
immunodeficiency virus (HIV)–associated tuberculosis in countries with a high disease …

A half-century of research on tuberculosis: Successes and challenges

BR Bloom - Journal of Experimental Medicine, 2023 - rupress.org
Great progress has been made over the past half-century, but TB remains a formidable
global health problem, particularly in low-and middle-income countries. Understanding the …

Host blood protein biomarkers to screen for tuberculosis disease: a systematic review and meta-analysis

M Gaeddert, K Glaser, BH Chendi… - Journal of Clinical …, 2024 - journals.asm.org
Non-sputum tests are needed to improve tuberculosis (TB) diagnosis and close the
diagnostic gap. The World Health Organization's target product profile (TPP) for point-of-care …

A Prospective Evaluation of the Diagnostic Accuracy of the Point-of-Care VISITECT CD4 Advanced Disease Test in 7 Countries

T Gils, J Hella, BKM Jacobs, B Sossen… - The Journal of …, 2025 - academic.oup.com
Background CD4 measurement is pivotal in the management of advanced human
immunodeficiency virus (HIV) disease. VISITECT CD4 Advanced Disease (VISITECT; …

Rearranging fluorescence‐magneto spatiality for “win‐win” dual functions to enhance point‐of‐care diagnosis

Y Su, X Chen, H Huang, Y Wu, X Shen, X Lin… - …, 2024 - Wiley Online Library
Fluorescent‐magneto nanoemitters have gained considerable attention for their applications
in mechanical controlling‐assisted optical signaling. However, the incompatibility between …

Diagnostic value of chemiluminescence for urinary lipoarabinomannan antigen assay in active tuberculosis: insights from a retrospective study

L Huang, Y Niu, L Zhang, R Yang… - Frontiers in Cellular and …, 2023 - frontiersin.org
Purpose This study aimed to assess the efficacy of chemiluminescence-based urinary
lipoarabinomannan (LAM) antigen assay as a diagnostic tool for identifying active …

Diagnostic yield as an important metric for the evaluation of novel tuberculosis tests: rationale and guidance for future research

T Broger, FM Marx, G Theron, BJ Marais… - The Lancet Global …, 2024 - thelancet.com
Better access to tuberculosis testing is a key priority for fighting tuberculosis, the leading
cause of infectious disease deaths in people. Despite the roll-out of molecular WHO …

Urine-Xpert Ultra for the diagnosis of tuberculosis in people living with HIV: a prospective, multicentre, diagnostic accuracy study

B Sossen, R Székely, M Mukoka, M Muyoyeta… - The Lancet Global …, 2024 - thelancet.com
Background Diagnostic delays for tuberculosis are common, with high resultant mortality.
Urine-Xpert Ultra (Cepheid) could improve time to diagnosis of tuberculosis disease and …

Real-world diagnostic accuracy of lipoarabinomannan in three non-sputum biospecimens for pulmonary tuberculosis disease

PK Drain, X Niu, AE Shapiro, ZP Magcaba, Z Ngcobo… - Ebiomedicine, 2024 - thelancet.com
Background Development of a non-sputum test using readily-obtainable biospecimens
remains a global priority for tuberculosis (TB) control. We quantified lipoarabinomannan …

[책][B] The challenge of tuberculosis in the 21st century: ERS monograph 101

AL García-Basteiro, FÖ Eyüboglu, MX Rangaka - 2023 - books.google.com
Recent years have witnessed key developments in the diagnosis and treatment of
tuberculosis. Alongside this, and running in direct opposition to this progress, was the …