C− H oxyfunctionalisation remains a distinct challenge for synthetic organic chemists.
Oxygenases and peroxygenases (grouped here as “oxygenating biocatalysts”) catalyse the …

Hydroxylated aromatic compounds exhibit exceptional biological activities. In the
biosynthesis of these compounds, three types of hydroxylases are commonly employed …

Plant-derived cytochrome P450-dependent flavonoid 3′-hydroxylases are the rate-limiting
enzymes in flavonoid biosynthesis. In this study, the large component (HpaB) of a …

Tyramine has attracted considerable interest due to recent findings that it is an excellent
starting material for the production of high-performance thermoplastics and hydrogels …

Catechols have important applications in the pharmaceutical, food, cosmetic, and functional
material industries. 4-hydroxyphenylacetate-3-hydroxylase (4HPA3H), a two-component …

4-Hydroxyphenylacetate 3-hydroxylase (4HPA3H) is a long-known class of two-component
flavin-dependent monooxygenases from bacteria, including an oxygenase component (EC …

Dihydroxyphenylacetate (DHPA) 2, 3-dioxygenase (EC 1.13. 11.15) from Acinetobacter
baumannii (Ab DHPAO) is an enzyme that catalyzes the 2, 3-extradiol ring-cleavage of …

HadA is a flavin-dependent monooxygenase catalyzing hydroxylation plus dehalogenation/
denitration, which is useful for biodetoxification and biodetection. In this study, the X-ray …

Flavin reductases play a vital role in catalyzing the reduction of flavin through NADH or
NADPH oxidation. The gene encoding flavin reductase from the thermophilic bacterium …

Bacterial luciferase (Lux) catalyzes a bioluminescence reaction by using long‐chain
aldehyde, reduced flavin and molecular oxygen as substrates. The reaction can be applied …