DDX RNA helicases: key players in cellular homeostasis and innate antiviral immunity

I Tapescu, S Cherry - Journal of Virology, 2024 - journals.asm.org
ABSTRACT RNA helicases are integral in RNA metabolism, performing important roles in
cellular homeostasis and stress responses. In particular, the DExD/H-box (DDX) helicase …

Noncanonical binding of transcription factors: time to revisit specificity?

MAH Samee - Molecular Biology of the Cell, 2023 - molbiolcell.org
Transcription factors (TFs) are one of the most studied classes of DNA-binding proteins that
have a direct functional impact on gene transcription and thus, on human physiology and …

EndoQuad: a comprehensive genome-wide experimentally validated endogenous G-quadruplex database

SH Qian, MW Shi, YL **ong, Y Zhang… - Nucleic Acids …, 2024 - academic.oup.com
Abstract G-quadruplexes (G4s) are non-canonical four-stranded structures and are
emerging as novel genetic regulatory elements. However, a comprehensive genomic …

In vivo detection of DNA secondary structures using Permanganate/S1 Footprinting with Direct Adapter Ligation and Sequencing (PDAL-Seq)

A Lahnsteiner, SJC Craig, K Kamali… - Methods in …, 2024 - Elsevier
DNA secondary structures are essential elements of the genomic landscape, playing a
critical role in regulating various cellular processes. These structures refer to G …

[HTML][HTML] The impact of chromatin on double-strand break repair: Imaging tools and discoveries

MAE van Bueren, A Janssen - DNA repair, 2024 - Elsevier
Eukaryotic nuclei are constantly being exposed to factors that break or chemically modify the
DNA. Accurate repair of this DNA damage is crucial to prevent DNA mutations and maintain …

[PDF][PDF] DNA markers and microsatellite code

VI Glazko, GY Kosovsky, TT Glazko… - Sel' …, 2023 - agrobiology.ru
The search for genetic markers that simplify the selection of animals for crosses, increasing
the likelihood of offspring obtaining with the desired manifestation of economically valuable …

Computational analysis on the dissemination of non-B DNA structural motifs in promoter regions of 1180 cellular genomes

VR Yella, A Vanaja - Biochimie, 2023 - Elsevier
The promoter regions of gene regulation are under evolutionary constraints and earlier
studies uncovered that they are characterized by enrichment of functional non-B DNA …

[HTML][HTML] ДНК маркеры и «микросателлитный код»(обзор)

ВИ Глазко, ГЮ Косовский, ТТ Глазко… - …, 2023 - agrobiology.ru
Одной из центральных проблем в современном животноводстве остается поиск
генетических маркеров, которые упростили бы отбор и подбор животных для …

Polymethine chain modified trimethine cyanine based fluorescent probe to selectively light up G-quadruplexes DNA in mitochondria

L Guan, Y Mao, Y Zhou, Y Fu, A Li, J Mei, H Zhou… - Dyes and …, 2023 - Elsevier
Abstract G-quadruplex (G4) is a noncanonical nucleic acid secondary structure that has
been demonstrated to have an impact on many physiological and pathological processes …

Evolutionary feedback from the environment shapes mechanisms that generate genome variation

LH Caporale - The Journal of Physiology, 2024 - Wiley Online Library
Darwin recognized that 'a grand and almost untrodden field of inquiry will be opened, on the
causes and laws of variation.'However, because the Modern Synthesis assumes that the …