Neurocognitive outcome of children exposed to perinatal mother-to-child Chikungunya virus infection: the CHIMERE cohort study on Reunion Island

P Gérardin, S Sampériz, D Ramful… - PLoS neglected …, 2014 - journals.plos.org
Background Little is known about the neurocognitive outcome in children exposed to
perinatal mother-to-child Chikungunya virus (p-CHIKV) infection. Methods The CHIMERE …

Activation of the PI3K-AKT pathway by old world alphaviruses

E Van Huizen, GM McInerney - Cells, 2020 - mdpi.com
Alphaviruses can infect a broad range of vertebrate hosts, including birds, horses, primates,
and humans, in which infection can lead to rash, fever, encephalitis, and arthralgia or …

A review of omics studies on arboviruses: alphavirus, orthobunyavirus and phlebovirus

RS Peinado, RJ Eberle, RK Arni, MA Coronado - Viruses, 2022 - mdpi.com
Since the intricate and complex steps in pathogenesis and host-viral interactions of
arthropod-borne viruses or arboviruses are not completely understood, the multi-omics …

The alphavirus nonstructural protein 2 NTPase induces a host translational shut-off through phosphorylation of eEF2 via cAMP-PKA-eEF2K signaling

EE Treffers, A Tas, FEM Scholte, AH de Ru… - PLoS …, 2023 - journals.plos.org
Chikungunya virus (CHIKV) is a reemerging alphavirus. Since 2005, it has infected millions
of people during outbreaks in Africa, Asia, and South/Central America. CHIKV replication …

Critical role for bone marrow stromal antigen 2 in acute Chikungunya virus infection

WD Mahauad-Fernandez… - Journal of General …, 2014 - microbiologyresearch.org
Bone marrow stromal antigen 2 (BST-2; also known as tetherin or CD317) is an IFN-
inducible gene that functions to block the release of a range of nascent enveloped virions …

Sphingosine kinase 2 is a chikungunya virus host factor co-localized with the viral replication complex

SP Reid, SR Tritsch, K Kota, CY Chiang… - Emerging microbes & …, 2015 - Taylor & Francis
Chikungunya virus (CHIKV) is a re-emerging alphavirus which causes severe and
prolonged arthralgic febrile illness. The recent global spread of the virus and lack of …

Magnetic fractionation and proteomic dissection of cellular organelles occupied by the late replication complexes of Semliki Forest virus

M Varjak, S Saul, L Arike, A Lulla, L Peil… - Journal of virology, 2013 - Am Soc Microbiol
Alphavirus replicase complexes are initially formed at the plasma membrane and are
subsequently internalized by endocytosis. During the late stages of infection, viral replication …

[HTML][HTML] Chikungunya and Mayaro Viruses Induce Chronic Skeletal Muscle Atrophy Triggered by Pro-Inflammatory and Oxidative Response

MOL da Silva, CM Figueiredo, RLS Neris… - International Journal of …, 2024 - mdpi.com
Chikungunya (CHIKV) and Mayaro (MAYV) viruses are arthritogenic alphaviruses that
promote an incapacitating and long-lasting inflammatory muscle–articular disease. Despite …

Current understanding of the role of cholesterol in the life cycle of alphaviruses

IP Sousa Jr, CAM Carvalho, AMO Gomes - Viruses, 2020 - mdpi.com
Enveloped viruses rely on different lipid classes present in cell membranes to accomplish
several steps of their life cycle in the host. Particularly for alphaviruses, a medically important …

SAMHD1 enhances chikungunya and zika virus replication in human skin fibroblasts

S Wichit, R Hamel, A Zanzoni, F Diop, A Cribier… - International Journal of …, 2019 - mdpi.com
Chikungunya virus (CHIKV) and Zika virus (ZIKV) are emerging arboviruses that pose a
worldwide threat to human health. Currently, neither vaccine nor antiviral treatment to control …