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[HTML][HTML] Oral delivery of proteins and peptides: Challenges, status quo and future perspectives
Proteins and peptides (PPs) have gradually become more attractive therapeutic molecules
than small molecular drugs due to their high selectivity and efficacy, but fewer side effects …
than small molecular drugs due to their high selectivity and efficacy, but fewer side effects …
[HTML][HTML] Intestinal absorption study: Challenges and absorption enhancement strategies in improving oral drug delivery
The oral route is the most common and practical means of drug administration, particularly
from a patient's perspective. However, the pharmacokinetic profile of oral drugs depends on …
from a patient's perspective. However, the pharmacokinetic profile of oral drugs depends on …
'Green'nanotherapeutics from tea leaves for orally targeted prevention and alleviation of colon diseases
M Zu, D **e, BSB Canup, N Chen, Y Wang, R Sun… - Biomaterials, 2021 - Elsevier
Although synthesized nanotherapeutics (NTs) are attractive for the oral treatment of colon
diseases, their clinical translations are constrained by the unsatisfactory therapeutic …
diseases, their clinical translations are constrained by the unsatisfactory therapeutic …
Non-invasive delivery strategies for biologics
Biologics now constitute a significant element of available medical treatments. Owing to their
clinical and commercial success, biologics are a rapidly growing class and have become a …
clinical and commercial success, biologics are a rapidly growing class and have become a …
Nanocarriers transport across the gastrointestinal barriers: the contribution to oral bioavailability via blood circulation and lymphatic pathway
D Wang, Q Jiang, Z Dong, T Meng, F Hu, J Wang… - Advanced drug delivery …, 2023 - Elsevier
Oral administration is the preferred route of drug delivery in clinical practice due to its
noninvasiveness, safety, convenience, and high patient compliance. The gastrointestinal …
noninvasiveness, safety, convenience, and high patient compliance. The gastrointestinal …
pH‐responsive polymers for drug delivery: trends and opportunities
J Singh, P Nayak - Journal of polymer science, 2023 - Wiley Online Library
Polymer science has applications in biomedical engineering, prosthetics, surgical implants,
and prospective pharmaceutical excipients for drug delivery.“Intelligent or Smart Polymers” …
and prospective pharmaceutical excipients for drug delivery.“Intelligent or Smart Polymers” …
Improvement strategies for the oral bioavailability of poorly water-soluble flavonoids: An overview
J Zhao, J Yang, Y **e - International journal of pharmaceutics, 2019 - Elsevier
Although flavonoid compounds have various pharmacological applications, they generally
exhibit low oral bioavailability due to their poor aqueous solubility. To address this problem …
exhibit low oral bioavailability due to their poor aqueous solubility. To address this problem …
Bioavailability of bioactive peptides derived from food proteins across the intestinal epithelial membrane: A review
Abstract Background Bioactive peptides (BAPs) play a crucial physiological role in human
health. To exert their biological effects after oral administration, BAPs have to be transported …
health. To exert their biological effects after oral administration, BAPs have to be transported …
[HTML][HTML] Formulation, stabilisation and encapsulation of bacteriophage for phage therapy
Against a backdrop of global antibiotic resistance and increasing awareness of the
importance of the human microbiota, there has been resurgent interest in the potential use of …
importance of the human microbiota, there has been resurgent interest in the potential use of …
Antimicrobial peptides–Advances in development of therapeutic applications
The severe infection is becoming a significant health problem which threaten the lives of
patients and the safety and economy of society. In the way of finding new strategy …
patients and the safety and economy of society. In the way of finding new strategy …