From antimicrobial to anticancer peptides. A review
Antimicrobial peptides (AMPs) are part of the innate immune defense mechanism of many
organisms. Although AMPs have been essentially studied and developed as potential …
organisms. Although AMPs have been essentially studied and developed as potential …
[HTML][HTML] Antimicrobial peptides with selective antitumor mechanisms: prospect for anticancer applications
In the last several decades, there have been significant advances in anticancer therapy.
However, the development of resistance to cancer drugs and the lack of specificity related to …
However, the development of resistance to cancer drugs and the lack of specificity related to …
[HTML][HTML] Membrane-active host defense peptides–challenges and perspectives for the development of novel anticancer drugs
S Riedl, D Zweytick, K Lohner - Chemistry and physics of lipids, 2011 - Elsevier
Although much progress has been achieved in the development of cancer therapies in
recent decades, problems continue to arise particularly with respect to chemotherapy due to …
recent decades, problems continue to arise particularly with respect to chemotherapy due to …
The interaction of antimicrobial peptides with membranes
OG Travkova, H Moehwald, G Brezesinski - Advances in colloid and …, 2017 - Elsevier
The interaction of antimicrobial peptides (AMPs) with biological membranes is in the focus of
research since several years, and the most important features and modes of action of AMPs …
research since several years, and the most important features and modes of action of AMPs …
Antimicrobial Peptides with Anti-Candida Activity
Mycoses are accountable for millions of infections yearly worldwide. Invasive candidiasis is
the most usual, presenting a high morbidity and mortality. Candida albicans remains the …
the most usual, presenting a high morbidity and mortality. Candida albicans remains the …
Tumor cell membrane-targeting cationic antimicrobial peptides: novel insights into mechanisms of action and therapeutic prospects
There is an ongoing need for effective and targeted cancer treatments that can overcome the
detrimental side effects presented by current treatment options. One class of novel …
detrimental side effects presented by current treatment options. One class of novel …
On the selectivity and efficacy of defense peptides with respect to cancer cells
F Harris, SR Dennison, J Singh… - Medicinal research …, 2013 - Wiley Online Library
Here, we review potential determinants of the anticancer efficacy of innate immune peptides
(ACPs) for cancer cells. These determinants include membrane‐based factors, such as …
(ACPs) for cancer cells. These determinants include membrane‐based factors, such as …
[HTML][HTML] Cyclic tachyplesin I kills proliferative, non-proliferative and drug-resistant melanoma cells without inducing resistance
Acquired drug resistance is the major cause for disease recurrence in cancer patients, and
this is particularly true for patients with metastatic melanoma that carry a BRAF V600E …
this is particularly true for patients with metastatic melanoma that carry a BRAF V600E …
Anticancer β-hairpin peptides: membrane-induced folding triggers activity
C Sinthuvanich, AS Veiga, K Gupta… - Journal of the …, 2012 - ACS Publications
Several cationic antimicrobial peptides (AMPs) have recently been shown to display
anticancer activity via a mechanism that usually entails the disruption of cancer cell …
anticancer activity via a mechanism that usually entails the disruption of cancer cell …
[HTML][HTML] Arthropod venoms and cancer
TE Heinen, ABG da Veiga - Toxicon, 2011 - Elsevier
Many active principles produced by animals, plants and microorganisms have been
employed in the development of new drugs to treat diseases such as cancer. Among the …
employed in the development of new drugs to treat diseases such as cancer. Among the …