Introduction: The hybridization of biologically active molecules is a powerful tool for drug
discovery used to target a variety of diseases. It offers the prospect of better drugs for the …

Cancer is one of the most deadly diseases that annually kills millions of people worldwide.
The investigation on anticancer medicines has never ceased to seek better and more …

Background Preoperative prediction of epidermal growth factor receptor (EGFR) mutation
status in patients with spinal bone metastases (SBM) from primary lung adenocarcinoma is …

Abstract Background Epidermal Growth Factor Receptor (EGFR) is a well-characterized
cancer drug target. In the past, several QSAR models have been developed for predicting …

Hepatitis C constitutes an unresolved global health problem. This infectious disease is
caused by the hepatotropic hepatitis C virus (HCV), and it can lead to the occurrence of life …

Viral infections constantly jeopardize the global public health due to lack of effective antiviral
therapeutics. Therefore, there is an imperative need to speed up the drug discovery process …

Epidermal growth factor receptor (EGFR) is an important validated drug target for cancer
therapy. Some therapeutic agents targeting EGFR have been developed, however these are …

The proteins within the human epidermal growth factor receptor (EGFR) family, members of
the tyrosine kinase receptor family, play a pivotal role in the molecular mechanisms driving …

Background Proinflammatory cytokines are correlated with the severity of disease in patients
with COVID-19. IL6-mediated activation of STAT3 proliferates proinflammatory responses …

Background In past, numerous quantitative structure-activity relationship (QSAR) based
models have been developed for predicting anticancer activity for a specific class of …