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[HTML][HTML] Exposure to polycyclic aromatic hydrocarbons with special focus on cancer
Polycyclic aromatic hydrocarbons (PAHs) are a group of compounds consisting of two or
more fused aromatic rings. Most of them are formed during incomplete combustion of …
more fused aromatic rings. Most of them are formed during incomplete combustion of …
The mitochondrial translocator protein (TSPO, 18ákDa): A key multifunctional molecule in liver diseases
Translocator protein (TSPO, 18ákDa), previously known as peripheral-type benzodiazepine
receptor, is an evolutionarily conserved and tryptophan-rich 169-amino-acid protein located …
receptor, is an evolutionarily conserved and tryptophan-rich 169-amino-acid protein located …
Optimisation of the extraction of crude polysaccharides from Clinacanthus nutans leaves for antioxidant applications: Content analysis, chemometrics and …
This study aimed to evaluate the optimal method for extracting crude polysaccharides from
Clinacanthus nutans leaves (CNP) as natural antioxidants. Five different extraction methods …
Clinacanthus nutans leaves (CNP) as natural antioxidants. Five different extraction methods …
[HTML][HTML] Preventive effect of D-carvone during DMBA induced mouse skin tumorigenesis by modulating xenobiotic metabolism and induction of apoptotic events
T Gopalakrishnan, S Ganapathy, V Veeran… - Biomedicine & …, 2019 - Elsevier
The structural integrity and excellent immune system of the skin makes it a protective
covering, inspite of its exposure to hazardous compounds. In the present study, the …
covering, inspite of its exposure to hazardous compounds. In the present study, the …
Altered histone abundance as a mode of ovotoxicity during 7, 12-dimethylbenz [a] anthracene exposure with additive influence of obesity
Histones are slowly evolving chromatin components and chromatin remodeling can
incorporate histone variants differing from canonical histones as an epigenetic modification …
incorporate histone variants differing from canonical histones as an epigenetic modification …
Inhibition of epigenetic modifiers LSD1 and HDAC1 blocks rod photoreceptor death in mouse models of retinitis pigmentosa
EY Popova, YI Kawasawa, SSM Zhang… - Journal of …, 2021 - jneurosci.org
Epigenetic modifiers are increasingly being investigated as potential therapeutics to modify
and overcome disease phenotypes. Diseases of the nervous system present a particular …
and overcome disease phenotypes. Diseases of the nervous system present a particular …
Butyrate inhibits the mitochondrial complex Ι to mediate mitochondria-dependent apoptosis of cervical cancer cells
K Zhang, X Ji, Z Song, W Song, Q Huang, T Yu… - … medicine and therapies, 2023 - Springer
Background Cervical cancer (CC) is a common gynecological malignancy with high
morbidity worldwide. Butyrate, a short-chain fatty acid produced by intestinal flora, has been …
morbidity worldwide. Butyrate, a short-chain fatty acid produced by intestinal flora, has been …
Obesity partially potentiates dimethylbenz [a] anthracene-exposed ovotoxicity by altering the DNA damage repair response in mice
Obesity adversely affects reproduction, impairing oocyte quality, fecundity, conception, and
implantation. The ovotoxicant, dimethylbenz [a] anthracene, is biotransformed into a …
implantation. The ovotoxicant, dimethylbenz [a] anthracene, is biotransformed into a …
Histone deacetylase 1 is essential for rod photoreceptor differentiation by regulating acetylation at histone H3 lysine 9 and histone H4 lysine 12 in the mouse retina
Histone acetylation has a regulatory role in gene expression and is necessary for proper
tissue development. To investigate the specific roles of histone deacetylases (HDACs) in rod …
tissue development. To investigate the specific roles of histone deacetylases (HDACs) in rod …
Differential microRNAs Expression during Cancer Development, and Chemoprevention by Natural Compounds: A Comprehensive Review
C Pandey, P Tiwari - Journal of Environmental Pathology …, 2024 - dl.begellhouse.com
MicroRNAs are short non-coding RNAs that inhibit gene expression at the post-
transcriptional level. Abnormal microRNA expression has been associated with different …
transcriptional level. Abnormal microRNA expression has been associated with different …