Utilization of polymers as biomaterials has greatly impacted the advancement of modern
medicine. Specifically, polymeric biomaterials that are biodegradable provide the significant …

In the treatment of health related dysfunctions, it is desirable that the drug reaches its site of
action at a particular concentration and that this therapeutic dose range remains constant …

The concept of tissue and cell guidance is rapidly evolving as more information regarding
the effect of the microenvironment on cellular function and tissue morphogenesis become …

Recent decades have seen great advancements in medical research into materials, both
natural and synthetic, that facilitate the repair and regeneration of compromised tissues …

Most FDA-approved adjuvants for infectious agents boost humoral but not cellular immunity,
and have poorly-understood mechanisms. Stimulator of interferon genes (STING, also …

For humans, companion animals, and food producing animals, vaccination has been touted
as the most successful medical intervention for the prevention of disease in the twentieth …

Vaccine development has progressed significantly and has moved from whole
microorganisms to subunit vaccines that contain only their antigenic proteins. Subunit …

Pancreatic cancer (PC) is the fourth leading cause of cancer-related deaths in the US,
claiming approximately 43,000 lives every year. Much like other solid tumors, PC evades the …

This review discusses the current status of chitosan and its derivatives as adjuvants and
delivery systems in vaccine delivery, and their future possibilities and challenges. After a …

Targeting pathogen recognition receptors on dendritic cells (DCs) offers the advantage of
triggering specific signaling pathways to induce a tailored and robust immune response. In …