Cellular barcodes are distinct DNA sequences that enable one to track specific cells across
time or space. Recent advances in our ability to detect natural or synthetic cellular barcodes …

Intratumor heterogeneity may result from the evolution of tumor cells and their continuous
interactions with the tumor microenvironment which collectively drives tumorigenesis …

The development of cancer begins with cells transitioning from their multicellular nature to a
state akin to unicellular organisms. This shift leads to a breakdown in the crucial regulators …

Cancer has been described as a genetic disease that clonally evolves in the face of
selective pressures imposed by cell-intrinsic and extrinsic factors. Although classical models …

Cancer will remain a global major health problem unless new diagnostic, prognostic, and
management approaches are discovered to address both loss of life and quality of life. Here …

Abstract Development of targeted therapies has significantly improved the prognosis of
patients with melanoma. Nevertheless, drug resistance is one of the most common …