Activation and signaling by the AMP-activated protein kinase in endothelial cells

B Fisslthaler, I Fleming - Circulation research, 2009 - Am Heart Assoc
The AMP-activated protein kinase (AMPK) was initially identified as the kinase that
phosphorylates the 3-hydroxy 3-methylglutaryl coenzyme A reductase, the rate-limiting …

Strategies for hypoxia adaptation in fish species: a review

CD Zhu, ZH Wang, B Yan - Journal of Comparative Physiology B, 2013 - Springer
Aquatic environments exhibit wide temporal and spatial variations in oxygen levels
compared to terrestrial environments. Fish are an excellent model for elucidating the …

Integrated analysis of mRNA-seq and miRNA-seq in the liver of Pelteobagrus vachelli in response to hypoxia

G Zhang, S Yin, J Mao, F Liang, C Zhao, P Li, G Zhou… - Scientific reports, 2016 - nature.com
Pelteobagrus vachelli is a well-known commercial species in Asia. However, a sudden lack
of oxygen will result in mortality and eventually to pond turnover. Studying the molecular …

Hypoxia tolerance in animals: biology and application

TA Gorr, D Wichmann, J Hu… - Physiological and …, 2010 - journals.uchicago.edu
Many invertebrates and ectothermic vertebrates successfully cope with a fluctuating supply
of ambient oxygen—and consequently, a highly variable tissue oxygenation—through …

AMP-activated protein kinase plays an important evolutionary conserved role in the regulation of glucose metabolism in fish skeletal muscle cells

LJ Magnoni, Y Vraskou, AP Palstra, JV Planas - PloS one, 2012 - journals.plos.org
AMPK, a master metabolic switch, mediates the observed increase of glucose uptake in
locomotory muscle of mammals during exercise. AMPK is activated by changes in the …

[HTML][HTML] Acute hypoxia and reoxygenation induces oxidative stress, glycometabolism, and oxygen transport change in red swamp crayfish (Procambarus clarkii) …

L Zhang, Z Song, S Zhong, J Gan, H Liang, Y Yu… - Aquaculture …, 2022 - Elsevier
Red swamp crayfish (Procambarus clarkii), an economically and ecologically important
crustacean, frequently encounter hypoxic environments in burrows or aquatic habitats …

Effects of environmental hypoxia on cardiac energy metabolism and performance in tilapia

B Speers-Roesch, E Sandblom… - American Journal …, 2010 - journals.physiology.org
The ability of an animal to depress ATP turnover while maintaining metabolic energy
balance is important for survival during hypoxia. In the present study, we investigated the …

Sensing and responding to energetic stress: Evolution of the AMPK network

PM Craig, CD Moyes, CMR LeMoine - Comparative Biochemistry and …, 2018 - Elsevier
AMP-activated protein kinase is an enzyme that mediates communication between cellular
energy status and diverse effector proteins, particularly those that play roles in determining …

Mitochondria: a multimodal hub of hypoxia tolerance

ME Pamenter - Canadian journal of zoology, 2014 - cdnsciencepub.com
Decreased oxygen availability impairs cellular energy production and, without a coordinated
and matched decrease in energy consumption, cellular and whole organism death rapidly …

The metabolic consequences of hepatic AMP-kinase phosphorylation in rainbow trout

S Polakof, S Panserat, PM Craig, DJ Martyres… - PloS one, 2011 - journals.plos.org
AMP-activated protein kinase (AMPK), a phylogenetically conserved serine/threonine
protein kinase, is proposed to function as a “fuel gauge” to monitor cellular energy status in …