Monoligated palladium (0) species, L1Pd (0), have emerged as the most active catalytic
species in the cross-coupling cycle. Today, there are methods available to generate the …

Pd-catalyzed cross-coupling reactions that form C–N bonds have become useful methods to
synthesize anilines and aniline derivatives, an important class of compounds throughout …

Synthetic organic chemistry experienced a significant advance in the last quarter of the 20th
century with the advent of the transition-metal catalyzed cross-coupling reactions. The utility …

Metal‐catalyzed cross‐coupling reactions belong to the most important transformations in
organic synthesis. Copper catalysis has received great attention owing to the low toxicity …

Click chemistry, proposed nearly 20 years ago, promised access to novel chemical space by
empowering combinatorial library synthesis with a “few good reactions”. These click …

A brief account of the major developments of palladium-catalyzed cross-coupling during the
last two decades is highlighted chronologically, with an emphasis on the personal …

An automated, droplet-flow microfluidic system explores and optimizes Pd-catalyzed Suzuki–
Miyaura cross-coupling reactions. A smart optimal DoE-based algorithm is implemented to …

In the light of the recent potentials of deuterated molecules as pharmaceuticals or even in
mechanistic understanding, efficient methods for their synthesis are continually desired …

The Ni-catalyzed Csp2–N cross-coupling of NH substrates and (hetero) aryl (pseudo)
halides for the synthesis of (hetero) anilines is in the midst of a resurgence. Reactivity …

Die metallkatalysierte Kreuzkupplung ist eine der wichtigsten Umwandlungen der
organischen Synthese. Aufgrund der geringen Toxizität und des günstigen Preises von …