Fractones: extracellular matrix niche controlling stem cell fate and growth factor activity in the brain in health and disease

F Mercier - Cellular and molecular life sciences, 2016 - Springer
The stem cell niche refers to a specific microenvironment where stem cells proliferate and
differentiate to produce new specialized cells throughout an organism's adulthood. Growth …

The aged brain: genesis and fate of residual progenitor cells in the subventricular zone

V Capilla-Gonzalez, V Herranz-Pérez… - Frontiers in cellular …, 2015 - frontiersin.org
Neural stem cells (NSCs) persist in the adult mammalian brain through life. The
subventricular zone (SVZ) is the largest source of stem cells in the nervous system, and …

Acquired hydrocephalus is associated with neuroinflammation, progenitor loss, and cellular changes in the subventricular zone and periventricular white matter

M Garcia-Bonilla, L Castaneyra-Ruiz, S Zwick… - Fluids and barriers of the …, 2022 - Springer
Background Hydrocephalus is a neurological disease with an incidence of 80–125 per
100,000 births in the United States. Neuropathology comprises ventriculomegaly …

Optimal extracellular matrix niches for neurogenesis: identifying glycosaminoglycan chain composition in the subventricular neurogenic zone

A Kerever, E Arikawa-Hirasawa - Frontiers in Neuroanatomy, 2021 - frontiersin.org
In the adult mammalian brain, new neurons are generated in a restricted region called the
neurogenic niche, which refers to the specific regulatory microenvironment of neural stem …

Human cord blood derived unrestricted somatic stem cells restore aquaporin channel expression, reduce inflammation and inhibit the development of hydrocephalus …

D Purohit, DA Finkel, A Malfa, Y Liao… - Frontiers in Cellular …, 2021 - frontiersin.org
Intraventricular hemorrhage (IVH) is a severe complication of preterm birth associated with
cerebral palsy, intellectual disability, and commonly, accumulation of cerebrospinal fluid …

A novel experimental animal model of adult chronic hydrocephalus

I Jusué-Torres, LH Jeon, EW Sankey, J Lu… - …, 2016 - journals.lww.com
BACKGROUND: The pathogenesis of adult chronic hydrocephalus is not fully understood,
and the temporal relationship between development of the radiological changes and …

Erythropoietin protects the subventricular zone and inhibits reactive astrogliosis in kaolin-induced hydrocephalic rats

W Suryaningtyas, M Arifin, FA Rantam… - Child's Nervous …, 2019 - Springer
Purpose To elucidate the potential role of erythropoietin (EPO) as a neuroprotective agent
against reactive astrogliosis and reducing the thinning rate of subventricular zone (SVZ) in …

The normalization trend of ventricular morphology after lateral ventricular tumor resection without additional diversion

H Jia, Z Bie, Y Fang, Z Gao, X Wang - Scientific Reports, 2024 - nature.com
Intraventricular tumors frequently provoke alterations in ventricular morphology. This study
aims to quantificational assess perioperative dynamic fluctuations in the cerebrospinal fluid …

Kidins220 sets the threshold for survival of neural stem cells and progenitors to sustain adult neurogenesis

A Del Puerto, C Lopez-Fonseca, A Simón-García… - Cell Death & …, 2023 - nature.com
In the adult mammalian brain, neural stem cells (NSCs) located in highly restricted niches
sustain the generation of new neurons that integrate into existing circuits. A reduction in …

Fractone aging in the subventricular zone of the lateral ventricle

A Kerever, T Yamada, Y Suzuki, F Mercier… - Journal of chemical …, 2015 - Elsevier
In adulthood, the subventricular zone (SVZ) is one of the restricted places where
neurogenesis persists. In this neurogenic niche, specialized extracellular matrix (ECM) …