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Fractones: extracellular matrix niche controlling stem cell fate and growth factor activity in the brain in health and disease
F Mercier - Cellular and molecular life sciences, 2016 - Springer
The stem cell niche refers to a specific microenvironment where stem cells proliferate and
differentiate to produce new specialized cells throughout an organism's adulthood. Growth …
differentiate to produce new specialized cells throughout an organism's adulthood. Growth …
The aged brain: genesis and fate of residual progenitor cells in the subventricular zone
Neural stem cells (NSCs) persist in the adult mammalian brain through life. The
subventricular zone (SVZ) is the largest source of stem cells in the nervous system, and …
subventricular zone (SVZ) is the largest source of stem cells in the nervous system, and …
Acquired hydrocephalus is associated with neuroinflammation, progenitor loss, and cellular changes in the subventricular zone and periventricular white matter
Background Hydrocephalus is a neurological disease with an incidence of 80–125 per
100,000 births in the United States. Neuropathology comprises ventriculomegaly …
100,000 births in the United States. Neuropathology comprises ventriculomegaly …
Optimal extracellular matrix niches for neurogenesis: identifying glycosaminoglycan chain composition in the subventricular neurogenic zone
In the adult mammalian brain, new neurons are generated in a restricted region called the
neurogenic niche, which refers to the specific regulatory microenvironment of neural stem …
neurogenic niche, which refers to the specific regulatory microenvironment of neural stem …
Human cord blood derived unrestricted somatic stem cells restore aquaporin channel expression, reduce inflammation and inhibit the development of hydrocephalus …
D Purohit, DA Finkel, A Malfa, Y Liao… - Frontiers in Cellular …, 2021 - frontiersin.org
Intraventricular hemorrhage (IVH) is a severe complication of preterm birth associated with
cerebral palsy, intellectual disability, and commonly, accumulation of cerebrospinal fluid …
cerebral palsy, intellectual disability, and commonly, accumulation of cerebrospinal fluid …
A novel experimental animal model of adult chronic hydrocephalus
BACKGROUND: The pathogenesis of adult chronic hydrocephalus is not fully understood,
and the temporal relationship between development of the radiological changes and …
and the temporal relationship between development of the radiological changes and …
Erythropoietin protects the subventricular zone and inhibits reactive astrogliosis in kaolin-induced hydrocephalic rats
Purpose To elucidate the potential role of erythropoietin (EPO) as a neuroprotective agent
against reactive astrogliosis and reducing the thinning rate of subventricular zone (SVZ) in …
against reactive astrogliosis and reducing the thinning rate of subventricular zone (SVZ) in …
The normalization trend of ventricular morphology after lateral ventricular tumor resection without additional diversion
H Jia, Z Bie, Y Fang, Z Gao, X Wang - Scientific Reports, 2024 - nature.com
Intraventricular tumors frequently provoke alterations in ventricular morphology. This study
aims to quantificational assess perioperative dynamic fluctuations in the cerebrospinal fluid …
aims to quantificational assess perioperative dynamic fluctuations in the cerebrospinal fluid …
Kidins220 sets the threshold for survival of neural stem cells and progenitors to sustain adult neurogenesis
A Del Puerto, C Lopez-Fonseca, A Simón-García… - Cell Death & …, 2023 - nature.com
In the adult mammalian brain, neural stem cells (NSCs) located in highly restricted niches
sustain the generation of new neurons that integrate into existing circuits. A reduction in …
sustain the generation of new neurons that integrate into existing circuits. A reduction in …
Fractone aging in the subventricular zone of the lateral ventricle
In adulthood, the subventricular zone (SVZ) is one of the restricted places where
neurogenesis persists. In this neurogenic niche, specialized extracellular matrix (ECM) …
neurogenesis persists. In this neurogenic niche, specialized extracellular matrix (ECM) …