Breast cancer exhibits various epigenetic abnormalities that regulate gene expression and
contribute to tumor characteristics. Epigenetic alterations play a significant role in cancer …

Background Inheritance patterns show familial clustering of gastrointestinal cancers, and
multiple germline conditions have now been identified that predispose to colorectal, gastric …

The burden of breast cancer continues to increase worldwide as it remains the most
diagnosed tumor in females and the second leading cause of cancer-related deaths. Breast …

Simple Summary The role of gender in oncology is an issue that is starting to be recognized
as being of extreme importance in the last few years. While breast cancer is commonly …

Background and purpose Diffuse midline glioma H3K27-altered (DMG) is an aggressive,
inoperable, predominantly paediatric brain tumour. Treatment strategies are limited …

Poly (ADP-ribose) polymerase inhibitors (PARPis) exhibit remarkable anticancer activity in
tumors with homologous recombination (HR) gene mutations. However, the role of other …

Background Breast cancer (BC) is a complex disease with various subtypes and genetic
alterations that impact DNA repair pathways. Understanding these pathways is essential for …

MAGI1 acts as a tumor suppressor in estrogen receptor-positive (ER+) breast cancer (BC),
and its loss correlates with a more aggressive phenotype. To identify the pathways and …

Globally, among numerous cancer subtypes, breast cancer (BC) is one of the most prevalent
forms of cancer affecting the female population. A female's family history significantly …

Introduction Since the mid-2000s, breast cancer incidence among women has slowly
increased at about 0.5% per year. In the last three decades, Breast Cancer Susceptibility …