Understanding hydrophobic effects: Insights from water density fluctuations

NB Rego, AJ Patel - Annual Review of Condensed Matter …, 2022 - annualreviews.org
The aversion of hydrophobic solutes for water drives diverse interactions and assemblies
across materials science, biology, and beyond. Here, we review the theoretical …

Intrusion and extrusion of liquids in highly confining media: Bridging fundamental research to applications

A Le Donne, A Tinti, E Amayuelas… - … in Physics: X, 2022 - Taylor & Francis
Wetting and drying of pores or cavities, made by walls that attract or repel the liquid, is a
ubiquitous process in nature and has many technological applications including, for …

Bionic Engineered Protein Coating Boosting Anti‐Biofouling in Complex Biological Fluids

Z Zhao, M Pan, C Qiao, L **ang, X Liu… - Advanced …, 2023 - Wiley Online Library
Implantable medical devices have been widely applied in diagnostics, therapeutics, organ
restoration, and other biomedical areas, but often suffer from dysfunction and infections due …

Identifying hydrophobic protein patches to inform protein interaction interfaces

NB Rego, E **, AJ Patel - Proceedings of the National …, 2021 - National Acad Sciences
Interactions between proteins lie at the heart of numerous biological processes and are
essential for the proper functioning of the cell. Although the importance of hydrophobic …

Contrasting changes in strongly and weakly bound hydration water of a protein upon denaturation

M Hishida, A Kaneko, Y Yamamura… - The Journal of Physical …, 2023 - ACS Publications
Water is considered integral for the stabilization and function of proteins, which has recently
attracted significant attention. However, the microscopic aspects of water ranging up to the …

Production of freeze-dried beef powder for complementary food: Effect of temperature control in retaining protein digestibility

S Lee, K Jo, YS Choi, S Jung - Food Chemistry, 2024 - Elsevier
This study investigated the effect of temperature control during freeze-drying of beef on the
in vitro protein digestibility. Frozen (at− 50° C for 2 days)-then-aged (at 4° C for 26 days) …

Learning the relationship between nanoscale chemical patterning and hydrophobicity

NB Rego, AL Ferguson… - Proceedings of the …, 2022 - National Acad Sciences
The hydrophobicity of proteins and similar surfaces, which display chemical heterogeneity at
the nanoscale, drives countless aqueous interactions and assemblies. However, predicting …

An affordable topography-based protocol for assigning a residue's character on a hydropathy (parch) scale

J Ji, B Carpentier, A Chakraborty… - Journal of Chemical …, 2023 - ACS Publications
The hydropathy of proteins or quantitative assessment of protein–water interactions has
been a topic of interest for decades. Most hydropathy scales use a residue-based or atom …

Using implicit-solvent potentials to extract water contributions to enthalpy–entropy compensation in biomolecular associations

S Chen, ZG Wang - The Journal of Physical Chemistry B, 2023 - ACS Publications
Biomolecular assembly typically exhibits enthalpy–entropy compensation (EEC) behavior
whose molecular origin remains a long-standing puzzle. While water restructuring is …

Comparative analysis of protein surface hydrophobicity maps determined by sparse sampling INDUS and spatial aggregation propensity

I Sinha, S Garde, SM Cramer - The Journal of Physical Chemistry …, 2023 - ACS Publications
Protein surface hydrophobicity plays a central role in various biological processes such as
protein folding and aggregation, as well as in the design and manufacturing of …