Characterizing natural recovery after traumatic spinal cord injury

S Kirshblum, B Snider, F Eren, J Guest - Journal of neurotrauma, 2021 - liebertpub.com
The predominant tool used to predict outcomes after traumatic spinal cord injury (SCI) is the
International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI), in …

[HTML][HTML] Pathophysiology, classification and comorbidities after traumatic spinal cord injury

J Guest, N Datta, G Jimsheleishvili… - Journal of personalized …, 2022 - mdpi.com
The spinal cord is a conduit within the central nervous system (CNS) that provides ongoing
communication between the brain and the rest of the body, conveying complex sensory and …

Safety and efficacy of riluzole in acute spinal cord injury study (RISCIS): a multi-center, randomized, placebo-controlled, double-blinded trial

MG Fehlings, A Moghaddamjou, JS Harrop… - Journal of …, 2023 - liebertpub.com
Riluzole is a sodium-glutamate antagonist that attenuates neurodegeneration in
amyotrophic lateral sclerosis (ALS). It has shown favorable results in promoting recovery in …

Application value of biofluid-based biomarkers for the diagnosis and treatment of spinal cord injury

HD Wang, ZJ Wei, JJ Li, SQ Feng - Neural Regeneration …, 2022 - journals.lww.com
Recent studies in patients with spinal cord injuries (SCIs) have confirmed the diagnostic
potential of biofluid-based biomarkers, as a topic of increasing interest in relation to SCI …

Independence and upper extremity functioning after spinal cord injury: a cross-sectional study

L Lili, KS Sunnerhagen, T Rekand, M Alt Murphy - Scientific Reports, 2023 - nature.com
Upper extremity functioning is important for achieving independence in activities of daily
living (ADL). A better understanding of relationships between different aspects of …

Body system effects of a multi-modal training program targeting chronic, motor complete thoracic spinal cord injury

KL Gant, KG Nagle, RE Cowan, EC Field-Fote… - Journal of …, 2018 - liebertpub.com
The safety and efficacy of pharmacological and cellular transplantation strategies are
currently being evaluated in people with spinal cord injury (SCI). In studies of people with …

A data-driven approach to categorize patients with traumatic spinal cord injury: cluster analysis of a multicentre database

S Basiratzadeh, R Hakimjavadi, N Baddour… - Frontiers in …, 2023 - frontiersin.org
Background Conducting clinical trials for traumatic spinal cord injury (tSCI) presents
challenges due to patient heterogeneity. Identifying clinically similar subgroups using patient …

Clinical and neurophysiological changes after targeted intrathecal injections of bone marrow stem cells in a C3 tetraplegic subject

AJ Santamaría, FD Benavides, DL DiFede… - Journal of …, 2019 - liebertpub.com
High-level quadriplegia is a devastating condition with limited treatment options. Bone
marrow derived stem cells (BMSCs) are reported to have immunomodulatory and …

Accuracy of self-reported severity and level of spinal cord injury

CL Furbish, RK Anderson, EC Field-Fote - Spinal Cord, 2022 - nature.com
Abstract Study design Observational. Objectives To assess accuracy of self-reported level of
injury (LOI) and severity in individuals with chronic spinal cord injury (SCI) as compared with …

Inter-rater reliability of the modified Medical Research Council scale in patients with chronic incomplete spinal cord injury

EB Dupépé, M Davis, GA Elsayed, B Agee… - Journal of neurosurgery …, 2019 - thejns.org
OBJECTIVE The aim of this study was to determine the inter-rater reliability of the modified
Medical Research Council (MRC) scale for grading motor function in patients with chronic …