Fat mass and obesity-associated protein (FTO) is the first reported RNA N6-
methyladenosine (m6A) demethylase in eukaryotic cells. m6A is considered as the most …

Over the last several years, the increasing prevalence of obesity has favored an intense
study of adipose tissue biology and the precise mechanisms involved in adipocyte …

Adipocytes are the defining cell type of adipose tissue. Once considered a passive
participant in energy storage, adipose tissue is now recognized as a dynamic organ that …

Breast cancer progression is highly dependent on the heterotypic interaction between tumor
cells and stromal cells of the tumor microenvironment. Cancer-associated adipocytes …

Obesity and diabetes affect more than half a billion individuals worldwide. Interestingly, the
two conditions do not always coincide and the molecular determinants of" healthy" versus" …

Diabetes, obesity, and cancer affect upward of 15% of the world's population. Interestingly,
all three diseases juxtapose dysregulated intracellular signaling with altered metabolic state …

Adipocytes play important roles in lipid storage, energy homeostasis and whole body insulin
sensitivity. The JAK–STAT (Janus Kinase–Signal Transducer and Activator of Transcription) …

The rising incidence of obesity and related disorders such as diabetes and heart disease
has focused considerable attention on the discovery of new therapeutics. One promising …

Obesity and diabetes represent key healthcare challenges of our day, affecting upwards of
one billion people worldwide. These individuals are at higher risk for cancer, stroke …

The biological relevance of cytokines is known for more than 20 years. Evidence suggests
that adipogenesis is one of the biological events involved in the regulation of cytokines, and …