Challenges in ARDS definition, management, and identification of effective personalized therapies

D Battaglini, B Fazzini, PL Silva, FF Cruz, L Ball… - Journal of Clinical …, 2023 - mdpi.com
Over the last decade, the management of acute respiratory distress syndrome (ARDS) has
made considerable progress both regarding supportive and pharmacologic therapies. Lung …

The use of extracorporeal CO2 removal in acute respiratory failure

R Giraud, C Banfi, B Assouline, A De Charrière… - Annals of intensive …, 2021 - Springer
Background Chronic obstructive pulmonary disease (COPD) exacerbation and protective
mechanical ventilation of acute respiratory distress syndrome (ARDS) patients induce …

Extracorporeal carbon dioxide removal for acute respiratory failure: a review of potential indications, clinical practice and open research questions

A Combes, D Brodie, N Aissaoui, T Bein… - Intensive Care …, 2022 - Springer
Extracorporeal carbon dioxide removal (ECCO2R) is a form of extracorporeal life support
(ECLS) largely aimed at removing carbon dioxide in patients with acute hypoxemic or acute …

Continuous renal replacement therapy and extended indications

C Ronco, T Reis - Seminars in dialysis, 2021 - Wiley Online Library
Extracorporeal blood purification (EBP) techniques provide support for critically ill patients
with single or multiple organ dysfunction. Continuous renal replacement therapy (CRRT) is …

[HTML][HTML] Ten golden rules for individualized mechanical ventilation in acute respiratory distress syndrome

D Battaglini, M Sottano, L Ball, C Robba… - Journal of Intensive …, 2021 - Elsevier
Considerable progress has been made over the last decades in the management of acute
respiratory distress syndrome (ARDS). Mechanical ventilation (MV) remains the cornerstone …

Extracorporeal Carbon Dioxide Removal to Avoid Invasive Ventilation During Exacerbations of Chronic Obstructive Pulmonary Disease: VENT-AVOID Trial–A …

A Duggal, SA Conrad, NA Barrett, M Saad… - American journal of …, 2024 - atsjournals.org
Rationale: It is unclear whether extracorporeal CO2 removal (ECCO2R) can reduce the rate
of intubation or the total time on invasive mechanical ventilation (IMV) in adults experiencing …

Antimicrobial exposure in critically ill patients with sepsis-associated multi-organ dysfunction requiring extracorporeal organ support: a narrative review

SL Cutuli, L Cascarano, P Lazzaro, ES Tanzarella… - Microorganisms, 2023 - mdpi.com
Sepsis is a leading cause of disability and mortality worldwide. The pathophysiology of
sepsis relies on the maladaptive host response to pathogens that fosters unbalanced organ …

Mechanical ventilation in patients with acute respiratory distress syndrome: current status and future perspectives

D Battaglini, IG Iavarone, C Robba, L Ball… - Expert Review of …, 2023 - Taylor & Francis
Introduction Although there has been extensive research on mechanical ventilation for acute
respiratory distress syndrome (ARDS), treatment remains mainly supportive. Recent studies …

Current knowledge gaps in extracorporeal respiratory support

T Tonetti, A Zanella, D Pérez-Torres, G Grasselli… - Intensive Care Medicine …, 2023 - Springer
Extracorporeal life support (ECLS) for acute respiratory failure encompasses veno-venous
extracorporeal membrane oxygenation (VV ECMO) and extracorporeal carbon dioxide …

Expert perspectives on ECCO2R for acute hypoxemic respiratory failure: consensus of a 2022 European roundtable meeting

A Combes, G Auzinger, L Camporota, G Capellier… - Annals of Intensive …, 2024 - Springer
Background By controlling hypercapnia, respiratory acidosis, and associated
consequences, extracorporeal CO2 removal (ECCO2R) has the potential to facilitate ultra …