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The SARS-CoV-2 nucleocapsid protein: its role in the viral life cycle, structure and functions, and use as a potential target in the development of vaccines and …
W Wu, Y Cheng, H Zhou, C Sun, S Zhang - Virology journal, 2023 - Springer
Abstract Coronavirus disease 2019 (COVID-19) continues to take a heavy toll on personal
health, healthcare systems, and economies around the globe. Scientists are expending …
health, healthcare systems, and economies around the globe. Scientists are expending …
COVID-19 vaccine update: vaccine effectiveness, SARS-CoV-2 variants, boosters, adverse effects, and immune correlates of protection
Abstract Coronavirus Disease 2019 (COVID-19) has been the most severe public health
challenge in this century. Two years after its emergence, the rapid development and …
challenge in this century. Two years after its emergence, the rapid development and …
Depleting myeloid-biased haematopoietic stem cells rejuvenates aged immunity
JB Ross, LM Myers, JJ Noh, MM Collins, AB Carmody… - Nature, 2024 - nature.com
Ageing of the immune system is characterized by decreased lymphopoiesis and adaptive
immunity, and increased inflammation and myeloid pathologies,. Age-related changes in …
immunity, and increased inflammation and myeloid pathologies,. Age-related changes in …
The biological and clinical significance of emerging SARS-CoV-2 variants
The past several months have witnessed the emergence of SARS-CoV-2 variants with novel
spike protein mutations that are influencing the epidemiological and clinical aspects of the …
spike protein mutations that are influencing the epidemiological and clinical aspects of the …
COVID-19 vaccine development: milestones, lessons and prospects
M Li, H Wang, L Tian, Z Pang, Q Yang… - Signal transduction and …, 2022 - nature.com
With the constantly mutating of SARS-CoV-2 and the emergence of Variants of Concern
(VOC), the implementation of vaccination is critically important. Existing SARS-CoV-2 …
(VOC), the implementation of vaccination is critically important. Existing SARS-CoV-2 …
Dynamics of antibody response to BNT162b2 vaccine after six months: a longitudinal prospective study
ABSTRACT Background SARS-CoV-2 mRNA vaccines have proven high efficacy, however,
limited data exists on the duration of immune responses and their relation to age and side …
limited data exists on the duration of immune responses and their relation to age and side …
SARS-CoV-2 B. 1.617. 2 Delta variant replication and immune evasion
Abstract The B. 1.617. 2 (Delta) variant of severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) was first identified in the state of Maharashtra in late 2020 and spread …
(SARS-CoV-2) was first identified in the state of Maharashtra in late 2020 and spread …
SARS-CoV-2 and innate immunity: the good, the bad, and the “goldilocks”
An ancient conflict between hosts and pathogens has driven the innate and adaptive arms of
immunity. Knowledge about this interplay can not only help us identify biological …
immunity. Knowledge about this interplay can not only help us identify biological …
Immunosenescence, aging and successful aging
Y Wang, C Dong, Y Han, Z Gu, C Sun - Frontiers in immunology, 2022 - frontiersin.org
Aging induces a series of immune related changes, which is called immunosenescence,
playing important roles in many age-related diseases, especially neurodegenerative …
playing important roles in many age-related diseases, especially neurodegenerative …
Effectiveness of the CoronaVac vaccine in older adults during a gamma variant associated epidemic of covid-19 in Brazil: test negative case-control study
Objective To estimate the effectiveness of the inactivated whole virus vaccine, CoronaVac
(Sinovac Biotech), against symptomatic covid-19 in the elderly population of São Paulo …
(Sinovac Biotech), against symptomatic covid-19 in the elderly population of São Paulo …