Clinical electroencephalography for anesthesiologists part I: background and basic signatures
The widely used electroencephalogram-based indices for depth-of-anesthesia monitoring
assume that the same index value defines the same level of unconsciousness for all …
assume that the same index value defines the same level of unconsciousness for all …
Burst suppression during general anesthesia and postoperative outcomes: mini review
N Pawar, OL Barreto Chang - Frontiers in Systems Neuroscience, 2022 - frontiersin.org
In the last decade, burst suppression has been increasingly studied by many to examine
whether it is a mechanism leading to postoperative cognitive impairment. Despite a lack of …
whether it is a mechanism leading to postoperative cognitive impairment. Despite a lack of …
Etiology of burst suppression EEG patterns
Burst-suppression electroencephalography (EEG) patterns of electrical activity,
characterized by intermittent high-power broad-spectrum oscillations alternating with …
characterized by intermittent high-power broad-spectrum oscillations alternating with …
[HTML][HTML] Nucleus accumbens neurons expressing dopamine D1 receptors modulate states of consciousness in sevoflurane anesthesia
WW Bao, W Xu, GJ Pan, TX Wang, Y Han, WM Qu… - Current Biology, 2021 - cell.com
Although general anesthesia (GA) enables patients to undergo surgery without
consciousness, the precise neural mechanisms underlying this phenomenon have yet to be …
consciousness, the precise neural mechanisms underlying this phenomenon have yet to be …
[HTML][HTML] Continuous action deep reinforcement learning for propofol dosing during general anesthesia
Purpose Anesthesiologists simultaneously manage several aspects of patient care during
general anesthesia. Automating administration of hypnotic agents could enable more …
general anesthesia. Automating administration of hypnotic agents could enable more …
Modulatory dynamics mark the transition between anesthetic states of unconsciousness
E Adam, O Kwon, KA Montejo, EN Brown - Proceedings of the National …, 2023 - pnas.org
Unconsciousness maintained by GABAergic anesthetics, such as propofol and sevoflurane,
is characterized by slow-delta oscillations (0.3 to 4 Hz) and alpha oscillations (8 to 14 Hz) …
is characterized by slow-delta oscillations (0.3 to 4 Hz) and alpha oscillations (8 to 14 Hz) …
[HTML][HTML] Orexin activated emergence from isoflurane anaesthesia involves excitation of ventral tegmental area dopaminergic neurones in rats
Background Orexin can facilitate emergence after general anaesthesia via multiple neural
pathways. Dopaminergic neurones in the ventral tegmental area (VTA) participate in …
pathways. Dopaminergic neurones in the ventral tegmental area (VTA) participate in …
Cerebellar Purkinje cell firing promotes conscious recovery from anesthesia state through coordinating neuronal communications with motor cortex
Background: The neurobiological basis of gaining consciousness from unconscious state
induced by anesthetics remains unknown. This study was designed to investigate the …
induced by anesthetics remains unknown. This study was designed to investigate the …
Cell-type-specific imaging of neurotransmission reveals a disrupted excitatory-inhibitory cortical network in isoflurane anaesthesia
Background Despite the fundamental clinical significance of general anaesthesia, the
cortical mechanism underlying anaesthetic-induced loss of consciousness (aLOC) remains …
cortical mechanism underlying anaesthetic-induced loss of consciousness (aLOC) remains …
[HTML][HTML] Duration of EEG suppression does not predict recovery time or degree of cognitive impairment after general anaesthesia in human volunteers
Background Burst suppression occurs in the EEG during coma and under general
anaesthesia. It has been assumed that burst suppression represents a deeper state of …
anaesthesia. It has been assumed that burst suppression represents a deeper state of …