Bone segmentation on whole-body CT using convolutional neural network with novel data augmentation techniques

S Noguchi, M Nishio, M Yakami, K Nakagomi… - Computers in biology …, 2020 - Elsevier
Background The purpose of this study was to develop and evaluate an algorithm for bone
segmentation on whole-body CT using a convolutional neural network (CNN). Methods …

Quantitative imaging of peripheral trabecular bone microarchitecture using MDCT

C Chen, X Zhang, J Guo, D **, EM Letuchy… - Medical …, 2018 - Wiley Online Library
Purpose Osteoporosis associated with reduced bone mineral density (BMD) and
microarchitectural changes puts patients at an elevated risk of fracture. Modern multidetector …

Finite element analysis of trabecular bone microstructure using CT imaging and continuum mechanical modeling

I Guha, X Zhang, CS Rajapakse, G Chang… - Medical …, 2022 - Wiley Online Library
Purpose Osteoporosis is a bone disease associated with enhanced bone loss,
microstructural degeneration, and fracture‐risk. Finite element (FE) modeling is used to …

Exploring Fracture Patterns: Assessing Representation Methods for Bone Fracture Simulation

FD Pérez-Cano, G Parra-Cabrera… - Journal of Personalized …, 2024 - mdpi.com
Fracture pattern acquisition and representation in human bones play a crucial role in
medical simulation, diagnostics, and treatment planning. This article presents a …

Bone fragment segmentation from 3D CT imagery

WG Shadid, A Willis - Computerized Medical Imaging and Graphics, 2018 - Elsevier
This paper presents a novel method to segment bone fragments imaged using 3D
Computed Tomography (CT). Existing image segmentation solutions often lack accuracy …

Method for Evaluating Cortical Bone Young's Modulus: Numerical Twin Reconstruction, Fe Calculation and Microstructure Analysis

T Kurtz, T Woitrain… - Journal of …, 2023 - asmedigitalcollection.asme.org
The determination of bone mechanical properties remains crucial, especially to feed up
numerical models. An original methodology of inverse analysis has been developed to …

Effects of fluoride intake on cortical and trabecular bone microstructure at early adulthood using multi-row detector computed tomography (MDCT)

PK Saha, RR Oweis, X Zhang, E Letuchy… - Bone, 2021 - Elsevier
Purpose The aim of this study was to examine the effects of period-specific and cumulative
fluoride (F) intake on bone at the levels of cortical and trabecular bone microstructural …

Quantitative CT Based Methods for Bone Microstructural Measures and Their Relationships With Vertebral Fractures in a Pilot Study on Smokers

X Zhang, AP Comellas, EA Regan… - Journal of Bone and …, 2021 - academic.oup.com
Osteoporosis causes fragile bone, and bone microstructural quality is a critical determinant
of bone strength and fracture risk. This study pursues technical validation of novel CT based …

Computed Tomography–based stiffness measures of trabecular bone microstructure: Cadaveric validation and in vivo application

I Guha, X Zhang, CS Rajapakse… - Journal of Bone and …, 2022 - academic.oup.com
Osteoporosis causes bone fragility and elevates fracture risk. Applications of finite element
(FE) analysis (FEA) for assessment of trabecular bone (Tb) microstructural strength at whole …

[HTML][HTML] Integrating deep learning and machine learning for improved CKD-related cortical bone assessment in HRpQCT images: A pilot study

Y Lee, WR Bandara, S Park, M Lee, C Seo, S Yang… - Bone Reports, 2025 - Elsevier
High resolution peripheral quantitative computed tomography (HRpQCT) offers detailed
bone geometry and microarchitecture assessment, including cortical porosity, but assessing …