Characterization of uterine leiomyomas by whole-genome sequencing

M Mehine, E Kaasinen, N Mäkinen… - … England Journal of …, 2013 - Mass Medical Soc
Background Uterine leiomyomas are benign but affect the health of millions of women. A
better understanding of the molecular mechanisms involved may provide clues to the …

SPOC domain-containing protein Leaf inclination3 interacts with LIP1 to regulate rice leaf inclination through auxin signaling

SH Chen, LJ Zhou, P Xu, HW Xue - PLoS genetics, 2018 - journals.plos.org
Leaf angle is an important agronomic trait and influences crop architecture and yield.
Studies have demonstrated the roles of phytohormones, particularly auxin and …

Functional and structural insights of the zinc-finger HIT protein family members involved in box C/D snoRNP biogenesis

B Bragantini, D Tiotiu, B Rothé, JM Saliou… - Journal of molecular …, 2016 - Elsevier
Zf–HIT family members share the zf–HIT domain (ZHD), which is characterized by a fold in
“treble-clef” through interleaved CCCC and CCHC ZnF motifs that both bind a zinc atom. Six …

Znhit1 and HIF-2α are correlated with cancer stem cell markers in breast cancer patients

SA Ebeid, NA Abd El Moneim, SA El-Benhawy… - Scientific Reports, 2022 - nature.com
Epigenetic alterations have emerged as fundamental players in development and
progression of breast cancer (BC). A hypoxic tumour microenvironment regulates the …

Proteomic sift through serum and endometrium profiles unraveled signature proteins associated with subdued fertility and dampened endometrial receptivity in women …

N Rashid, A Nigam, SK Jain, SH Naqvi, S Wajid - Cell and tissue research, 2020 - Springer
The objective of this study is to discern the proteomic differences responsible for hampering
the receptivity of endometrium and subduing the fertility of females with polycystic ovary …

RETRACTED: Znhit1 inhibits breast cancer by up-regulating PTEN to deactivate the PI3K/Akt/mTOR pathway

C Cui, S Li, D Wu - 2019 - Elsevier
Given the comments regarding this article “This paper belongs to a set of over 400 papers
(as per February 2020) that share very similar Western blots with tadpole-like shaped bands …

First insight into the kinome of human regulatory T cells

S König, M Probst-Kepper, T Reinl, A Jeron, J Huehn… - PLoS …, 2012 - journals.plos.org
Regulatory T cells (Tregs) are essential for controlling peripheral tolerance by the active
suppression of various immune cells including conventional T effector cells (Teffs) …

Chromatin remodeler Znhit1 controls bone morphogenetic protein signaling in embryonic lung tissue branching

W Wei, X Tang, N Jiang, C Ni, H He, S Sun… - Journal of Biological …, 2022 - ASBMB
Branching morphogenesis is a key process essential for lung and other organ development
in which cellular and tissue architecture branch out to maximize surface area. While this …

[PDF][PDF] Molecular cloning, characterization and association analysis of the promoter region of the bovine CDK6 gene

YF Liu, LS Zan, WT Cui, YP **n, Y Jiao, K Li - Genet. Mol. Res, 2011 - geneticsmr.com
Cyclin-dependent kinase 6 (CDK6) is a key element of D-type cyclin holoenzymes. It is
involved in the regulation of the G1-phase of the cell cycle and is considered to be an …

[HTML][HTML] Molecular classification of uterine leiomyomas by genome-wide methods

M Mehine - 2016 - helda.helsinki.fi
Uterine leiomyomas, often called fibroids, are highly common tumors arising from smooth
muscle cells of the myometrium. Whereas cancers have the ability to metastasize …