Vulval squamous cell carcinoma and its precursors

N Singh, CB Gilks - Histopathology, 2020 - Wiley Online Library
Vulval squamous cell carcinoma (VSCC) can arise through two distinct pathways [human
papillomavirus (HPV)‐associated and HPV‐independent], and these VSCC variants are …

British Gynaecological Cancer Society (BGCS) vulval cancer guidelines: Recommendations for practice

J Morrison, P Baldwin, L Buckley, L Cogswell… - European Journal of …, 2020 - Elsevier
The purpose of this guideline is to collate evidence and propose evidence-based guidelines
for the diagnosis and management of adult patients with vulva carcinoma treated in the UK …

[HTML][HTML] 2020 WHO classification of female genital tumors

AK Höhn, CE Brambs, GGR Hiller… - Geburtshilfe und …, 2021 - thieme-connect.com
In der WHO-Klassifikation 2020 steht die Unterscheidung von HPV-assoziierten und HPV-
unabhängigen Plattenepithelkarzinomen des unteren weiblichen Genitales im Vordergrund …

Major p53 immunohistochemical patterns in in situ and invasive squamous cell carcinomas of the vulva and correlation with TP53 mutation status

B Tessier-Cloutier, KE Kortekaas, E Thompson… - Modern …, 2020 - nature.com
The recent literature has shown that vulvar squamous cell carcinoma (VSCC) can be
stratified into two prognostically relevant groups based on human papillomavirus (HPV) …

British Gynaecological Cancer Society (BGCS) vulval cancer guidelines: An update on recommendations for practice 2023

J Morrison, P Baldwin, L Hanna, A Andreou… - European Journal of …, 2024 - Elsevier
Evidence was searched in the Cochrane Central Register of Controlled Trials (CENTRAL,
The Cochrane Library April 2022, Issue 4), MEDLINE and EMBASE up to April 2022, with …

The prognostic significance of HPV, p16, and p53 protein expression in vaginal cancer: A systematic review

CL Rasmussen, HK Bertoli, FL Sand… - Acta obstetricia et …, 2021 - Wiley Online Library
Introduction Human papillomavirus (HPV), p16, and p53 have been investigated as
prognostic markers in various HPV‐related cancers. Within the field of vaginal cancer …

Immunohistochemistry in gynecologic carcinomas: Practical update with diagnostic and clinical considerations based on the 2020 WHO classification of tumors

N Buza - Seminars in Diagnostic Pathology, 2022 - Elsevier
This review provides an update on immunohistochemistry applications–diagnostic,
prognostic, and predictive–in the pathology evaluation of gynecologic carcinomas. The 5th …

p53 and p16 expression profiles in vulvar cancer: a translational analysis by the Arbeitsgemeinschaft Gynäkologische Onkologie Chemo and Radiotherapy in …

L Woelber, K Prieske, C Eulenburg… - American Journal of …, 2021 - Elsevier
Background There are 2 known pathways for tumorigenesis of vulvar squamous cell
carcinoma—a human papillomavirus–dependent pathway characterized by p16 …

Human papillomavirus prevalence, genotype distribution, and prognostic factors of vaginal cancer

HJ Tung, YC Wang, CY Lin, MJ Liao… - … Journal of Cancer, 2024 - Wiley Online Library
We aimed to investigate human papillomavirus (HPV) prevalence and genotype distribution
and prognostic factors in vaginal cancer (VC). VC patients who received treatment between …

Molecular pathways in vulvar squamous cell carcinoma: implications for target therapeutic strategies

G Mantovani, SM Fragomeni, F Inzani, A Fagotti… - Journal of cancer …, 2020 - Springer
Background Additional prognostic factors and personalized therapeutic alternatives for
vulvar squamous cell carcinoma (VSCC), especially for advanced stages with poor …