Centrosomes are microtubule-organizing centres of animal cells. They influence the
morphology of the microtubule cytoskeleton, function as the base for the primary cilium and …

Mitosis and cytokinesis are undoubtedly the most spectacular parts of the cell cycle. Errors in
the choreography of these processes can lead to aneuploidy or genetic instability, fostering …

Genetic screens for cell division cycle mutants in the filamentous fungus Aspergillus
nidulans led to the discovery of never-in-mitosis A (NIMA), a serine/threonine kinase that is …

We show that overexpression of Polo-like kinase 4 (Plk4) in human cells induces
centrosome amplification through the simultaneous generation of multiple procentrioles …

Centrioles are essential for the formation of cilia and flagella. They also form the core of the
centrosome, which organizes microtubule arrays important for cell shape, polarity, motility …

Using sequential gene expression profiling (GEP) samples, we defined a major functional
group related to drug resistance that contains chromosomal instability (CIN) genes. One CIN …

Primary cilia (PC) function as microtubule-based sensory antennae projecting from the
surface of many eukaryotic cells. They play important roles in mechano-and chemosensory …

First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
52460698&utm_source= google_patent&utm_medium= platform_link&utm_campaign …

Mammalian centrioles play a dynamic role in centrosome function, but they also have the
capacity to nucleate the assembly of cilia. Although controls must exist to specify these …

Aberrations in centrosome numbers have long been implicated in aneuploidy and
tumorigenesis, but their origins are unknown. Here we have examined how overexpression …