Idiopathic nephrotic syndrome in children

DG Noone, K Iijima, R Parekh - The Lancet, 2018 - thelancet.com
The incidence of idiopathic nephrotic syndrome (NS) is 1· 15–16· 9 per 100 000 children,
varying by ethnicity and region. The cause remains unknown but the pathogenesis of …

Nephrotic syndrome in infants and children: pathophysiology and management

ML Downie, C Gallibois, RS Parekh… - … and international child …, 2017 - Taylor & Francis
Nephrotic syndrome is defined by nephrotic-range proteinuria (≥ 40 mg/m2/hour or urine
protein/creatinine ratio≥ 200 mg/mL or 3+ protein on urine dipstick), hypoalbuminaemia (< …

Long-term efficacy and safety of repeated rituximab to maintain remission in idiopathic childhood nephrotic syndrome: an international study

EY Chan, LM Ellen, A Angeletti, Z Arslan… - Journal of the …, 2022 - journals.lww.com
Background Long-term outcomes after multiple courses of rituximab among children with
frequently relapsing, steroid-dependent nephrotic syndrome (FRSDNS) are unknown …

Use of rituximab in childhood idiopathic nephrotic syndrome

EY Chan, DY Yap, M Colucci, AL Ma… - Clinical Journal of the …, 2023 - journals.lww.com
Rituximab is an established therapy in children with idiopathic nephrotic syndrome to
sustain short-to medium-term disease remission and avoid steroid toxicities. Recent trials …

Interventions for idiopathic steroid‐resistant nephrotic syndrome in children

ID Liu, NS Willis, JC Craig… - Cochrane database of …, 2019 - cochranelibrary.com
Background The majority of children who present with their first episode of nephrotic
syndrome achieve remission with corticosteroid therapy. Children who fail to respond to …

Incidence and relapse of idiopathic nephrotic syndrome: meta-analysis

F Veltkamp, LR Rensma, AHM Bouts - Pediatrics, 2021 - publications.aap.org
Incidence and Relapse of Idiopathic Nephrotic Syndrome: Meta-analysis | Pediatrics | American
Academy of Pediatrics Skip to Main Content Disclaimer » Advertising AAP logo Search Close …

[HTML][HTML] Both the rituximab dose and maintenance immunosuppression in steroid-dependent/frequently-relapsing nephrotic syndrome have important effects on …

EY Chan, H Webb, E Yu, GM Ghiggeri, MJ Kemper… - Kidney international, 2020 - Elsevier
Rituximab is an effective treatment for steroid-dependent/frequently-relapsing nephrotic
syndrome (SDFRNS) in children. However, the optimal rituximab regimen remains unknown …

Rituximab use in the management of childhood nephrotic syndrome

M Kallash, WE Smoyer, JD Mahan - Frontiers in pediatrics, 2019 - frontiersin.org
Childhood nephrotic syndrome is a challenging and often persistent renal disorder, and its
incidence varies between different ethnicities and regions. Corticosteroids have been the …

Hypertension in childhood nephrotic syndrome

IF Shatat, LJ Becton, RP Woroniecki - Frontiers in pediatrics, 2019 - frontiersin.org
Arterial hypertension (HTN) is commonly encountered by clinicians treating children with
steroid sensitive (SSNS) and steroid resistant nephrotic syndrome (SRNS). Although the …

[HTML][HTML] Prediction of short-and long-term outcomes in childhood nephrotic syndrome

SA Carter, S Mistry, J Fitzpatrick, T Banh… - Kidney international …, 2020 - Elsevier
Introduction It is unknown whether steroid sensitivity and other putative risk factors collected
at baseline can predict the disease course of idiopathic nephrotic syndrome in childhood …