Circadian rhythms are near 24-h patterns of physiology and behaviour that are present
independent of external cues including hormones, body temperature, mood, and sleep …

Sleep disturbances and circadian rhythm dysfunction have been widely demonstrated in
patients with bipolar disorder (BD). Irregularity of the sleep–wake rhythm, eveningness …

Disturbances of sleep are typical for most depressed patients and belong to the core
symptoms of the disorder. Since the 1960s polysomnographic sleep research has …

Behavioral Genetics, Fifth Edition provides an engaging and clear overview of human and
animal behavioral genetics that is designed to introduce students in the behavioral …

Circadian cycles affect a variety of physiological processes, and disruptions of normal
circadian biology therefore have the potential to influence a range of disease-related …

Epigenetic information, which may affect an organism's phenotype, can be stored and stably
inherited in the form of cytosine DNA methylation. Changes in DNA methylation can produce …

Evidence is accumulating regarding the importance of circadian core oscillators, several
associated factors, and melatonin signaling in the maintenance of health. Dysfunction of …

Circadian rhythms and the genes that make up the molecular clock have long been
implicated in bipolar disorder. Genetic evidence in bipolar patients suggests that the central …

For many years, researchers have suggested that abnormalities in circadian rhythms may
underlie the development of mood disorders such as bipolar disorder (BPD), major …

Significance: Our current knowledge of the pathophysiology and molecular mechanisms
causing psychiatric disorders is modest, but genetic susceptibility and environmental factors …