The implications of exosomes in pregnancy: emerging as new diagnostic markers and therapeutics targets

M Ghafourian, R Mahdavi, Z Akbari Jonoush… - Cell Communication and …, 2022 - Springer
Extracellular vehicles (EVs) are a heterogeneous group of cell and membranous particles
originating from different cell compartments. EVs participate in many essential physiological …

Exosomes as messengers between mother and fetus in pregnancy

L Czernek, M Düchler - International Journal of Molecular Sciences, 2020 - mdpi.com
The ability of exosomes to transport different molecular cargoes and their ability to influence
various physiological factors is already well known. An exciting area of research explores …

Extracellular vesicles are dynamic regulators of maternal glucose homeostasis during pregnancy

HC Zierden, R Marx-Rattner, KD Rock… - Scientific reports, 2023 - nature.com
Homeostatic regulation of the maternal milieu during pregnancy is critical for maternal and
fetal health. The placenta facilitates critical communication between maternal and fetal …

Protein markers for Candida albicans EVs include claudin-like Sur7 family proteins

CS Dawson, D Garcia-Ceron… - Journal of …, 2020 - Taylor & Francis
ABSTRACT Background: Fungal extracellular vesicles (EVs) have been implicated in host-
pathogen and pathogen-pathogen communication in some fungal diseases. In depth …

HPV+ head and neck cancer–derived small extracellular vesicles communicate with TRPV1+ neurons to mediate cancer pain

KE Inyang, CM Evans, M Heussner, M Petroff… - Pain, 2024 - journals.lww.com
Severe pain is often experienced by patients with head and neck cancer and is associated
with a poor prognosis. Despite its frequency and severity, current treatments fail to …

Extracellular vesicles and immune response during pregnancy: A balancing act

AE Morelli, Y Sadovsky - Immunological reviews, 2022 - Wiley Online Library
The mechanisms underlying maternal tolerance of the semi‐or fully‐allogeneic fetus are
intensely investigated. Across gestation, feto‐placental antigens interact with the maternal …

Integrins mediate placental extracellular vesicle trafficking to lung and liver in vivo

SL Nguyen, SH Ahn, JW Greenberg, BW Collaer… - Scientific Reports, 2021 - nature.com
Membrane-bound extracellular vesicles (EVs) mediate intercellular communication in all
organisms, and those produced by placental mammals have become increasingly …

Placental small extracellular vesicles: Current questions and investigative opportunities

Y Sadovsky, Y Ouyang, JS Powell, H Li, JF Mouillet… - Placenta, 2020 - Elsevier
The discovery of regulated trafficking of extracellular vesicles (EVs) has added a new
dimension to our understanding of local and distant communication among cells and …

[HTML][HTML] Extracellular vesicles: Mediators of embryo-maternal crosstalk during pregnancy and a new weapon to fight against infertility

M Das, V Kale - European Journal of Cell Biology, 2020 - Elsevier
In modern-day life, infertility is one of the major issues that can affect an individual, both
physically and psychologically. Several anatomical, physiological, and genetic factors might …

Production and composition of group B streptococcal membrane vesicles vary across diverse lineages

CR McCutcheon, ME Pell, JA Gaddy… - Frontiers in …, 2021 - frontiersin.org
Although the neonatal and fetal pathogen Group B Streptococcus (GBS) asymptomatically
colonizes the vaginal tract of∼ 30% of pregnant women, only a fraction of their offspring …