The cell-free system: A new apparatus for affordable, sensitive, and portable healthcare

CE Copeland, A Langlois, J Kim, YC Kwon - Biochemical Engineering …, 2021 - Elsevier
The cell-free system is a tool that harnesses the complex biological processes outside of
living cells. Owing to the system's superior flexibility and manipulability, it has matured its …

Identification, characterization, and engineering of glycosylation in thrombolytics

M Toul, V Slonkova, J Mican, A Urminsky… - Biotechnology …, 2023 - Elsevier
Cardiovascular diseases, such as myocardial infarction, ischemic stroke, and pulmonary
embolism, are the most common causes of disability and death worldwide. Blood clot …

Diverse origins of fibrinolytic enzymes: A comprehensive review

C Hazare, P Bhagwat, S Singh, S Pillai - Heliyon, 2024 - cell.com
Fibrinolytic enzymes cleave fibrin which plays a crucial role in thrombus formation which
otherwise leads to cardiovascular diseases. While different fibrinolytic enzymes have been …

[HTML][HTML] Cavitation-assisted sonothrombolysis by asymmetrical nanostars for accelerated thrombolysis

W Choi, J Key, I Youn, H Lee, S Han - Journal of Controlled Release, 2022 - Elsevier
Sonothrombolysis with recombinant tissue plasminogen activator (rtPA) and microbubbles
has been widely studied to enhance thrombolytic potential. Here, we report different …

Cross-Talk of Atherosclerosis and Ischemic Stroke: Dramatic Role of Neutrophils

A Esmaeilzadeh, M Zarerafie… - Archives of …, 2021 - brieflands.com
Context: Current investigations illustrate the increasing prevalence of atherosclerosis (AS)
through the aggravating role of inappropriate lifestyle patterns. Atherosclerosis is the cause …

Targeted thrombolysis by magnetoacoustic particles in photothrombotic stroke model

W Choi, H Cho, G Kim, I Youn, J Key… - Biomaterials Research, 2022 - spj.science.org
Background Recombinant tissue plasminogen activator (rtPA) has a short half-life, and
additional hemorrhagic transformation (HT) can occur when treatment is delayed. Here, we …

“Cell-Free Synthetic Biology”: Synthetic Biology Meets Cell-Free Protein Synthesis

SH Hong - Methods and Protocols, 2019 - mdpi.com
Since Nirenberg and Matthaei used cell-free protein synthesis (CFPS) to elucidate the
genetic code in the early 1960s [1], the technology has been developed over the course of …

Engineering Cell-Free Protein Synthesis Biosensors for Point of Care Use

TJ Free - 2024 - scholarsarchive.byu.edu
Diagnostic tests can dramatically improve and save lives. Survival rates and patient
outcomes related to cancer and other diseases can be improved when routine testing …

Cell-free protein synthesis for on-site and on-demand biomanufacturing in extreme and low resource environments

T Shivakumar - 2023 - eprints.nottingham.ac.uk
Humans are starting to explore extreme environments such as space due to advancements
in Science and Technology. Although current manned missions have involved short …

Expanding the Mammalian Synthetic Biology Toolbox: Orthogonal Tools and Circuits for Cellular Reprogramming

B Bachhav - 2020 - search.proquest.com
Cell engineering presents great potential for next-generation biotechnological and
biomedical applications that employ engineered mammalian cells to sense intracellular or …