Recent advances in the targeted delivery of paclitaxel nanomedicine for cancer therapy

F Raza, H Zafar, MW Khan, A Ullah, AU Khan… - Materials …, 2022 - pubs.rsc.org
Cancer cases have reached an all-time high in the current era. Thus, there is a need to
develop advanced therapeutic methods that can effectively inhibit the proliferation of …

Recent progress on nanomedicine-induced ferroptosis for cancer therapy

H Zafar, F Raza, S Ma, Y Wei, J Zhang, Q Shen - Biomaterials Science, 2021 - pubs.rsc.org
The current treatment strategies for cancer therapy have posed many problems in achieving
high efficacy. Therefore, an urgent step is needed to develop innovative therapies that can …

Targeting cancer cells overexpressing folate receptors with new terpolymer-based nanocapsules: Toward a novel targeted dna delivery system for cancer therapy

E Bellotti, MG Cascone, N Barbani, D Rossin… - Biomedicines, 2021 - mdpi.com
Chemotherapeutics represent the standard treatment for a wide range of cancers. However,
these agents also affect healthy cells, thus leading to severe off-target effects. Given the non …

Recent advances of magnetic gold hybrids and nanocomposites, and their potential biological applications

GR Elmi, K Saleem, MMFA Baig, MN Aamir, M Wang… - Magnetochemistry, 2022 - mdpi.com
Magnetic gold nanoparticles (mGNP) have become a great interest of research for
nanomaterial scientists because of their significant magnetic and plasmonic properties …

A DNA nanodevice simultaneously activating the EGFR and integrin for enhancing cytoskeletal activity and cancer cell treatment

MMFA Baig, QW Zhang, MR Younis, XH **a - Nano Letters, 2019 - ACS Publications
Cell-surface receptors (eg, EGFR and integrin) and their interactions play determining roles
in signal transduction and cytoskeletal activation, which affect cell attachment/detachment …

[HTML][HTML] DNA nanotechnology as a tool to develop molecular tension probes for bio-sensing and bio-imaging applications: An up-to-date review

MMFA Baig, WF Lai, MF Akhtar, A Saleem… - Nano-Structures & Nano …, 2020 - Elsevier
DNA is known to be a life material that has been explored as an exciting biomaterial for bio-
sensing, bio-imaging, and analytical applications. The current review focuses on describing …

Self-assembly of DNA nanospheres with controllable size and self-degradable property for enhanced antitumor chemotherapy

H Liu, Y Zhang, Z Zhang, Z Deng, J Bu, T Li… - Colloids and Surfaces B …, 2023 - Elsevier
Controllable size, self-degradability and targeting property are important for a precise
improvement of anticancer effects and reduction of side effects of drug vehicles. Here, a …

Synthetic NRG-1 functionalized DNA nanospindels towards HER2/neu targets for in vitro anti-cancer activity assessment against breast cancer MCF-7 cells

MMFA Baig, WF Lai, R Mikrani, M Jabeen… - … of Pharmaceutical and …, 2020 - Elsevier
DNA based nano-carriers synthesized from short circular scaffolds (circular DNA
nanotechnology) attains stiffer topology for ligand functionalization (neuregulin-1/NRG-1 …

2D DNA nanoporous scaffold promotes osteogenic differentiation of pre-osteoblasts

MMFA Baig, WL Dissanayaka, C Zhang - International Journal of Biological …, 2021 - Elsevier
Biofunctional materials with nanomechanical parameters similar to bone tissue may promote
the adherence, migration, proliferation, and differentiation of pre-osteoblasts. In this study …

The integrin facilitated internalization of fibronectin-functionalized camptothecin-loaded DNA-nanofibers for high-efficiency anticancer effects

MMFA Baig, WF Lai, S Ashraf, A Saleem… - Drug Delivery and …, 2020 - Springer
Camptothecin (CMPT) in a free form is extremely cytotoxic as well as hydrophobic drug, and
is considered to be highly contagious for systemic administration. The fibronectin (FN) …