Significance of interleukin (IL)-4 and IL-13 in inflammatory arthritis

M Iwaszko, S Biały, K Bogunia-Kubik - Cells, 2021 - mdpi.com
Interleukin (IL)-4 and IL-13 belong to the T helper 2 (Th2) cytokine family, along with IL-3, IL-
5, and IL-9. These cytokines are key mediators of allergic inflammation. They have important …

The pathogenesis of psoriatic arthritis

DJ Veale, U Fearon - The Lancet, 2018 - thelancet.com
Psoriatic arthritis is a chronic, immune-mediated, inflammatory arthropathy that presents with
inflammation of the joints and entheses, including those of the axial skeleton, and is …

Psoriasis: classical and emerging comorbidities

MFSP Oliveira, BO Rocha, GV Duarte - Anais brasileiros de …, 2015 - SciELO Brasil
Psoriasis is a chronic inflammatory systemic disease. Evidence shows an association of
psoriasis with arthritis, depression, inflammatory bowel disease and cardiovascular …

[HTML][HTML] T helper 2 IL-4/IL-13 dual blockade with dupilumab is linked to some emergent T helper 17‒type diseases, including seronegative arthritis and enthesitis …

C Bridgewood, M Wittmann, T Macleod, A Watad… - Journal of Investigative …, 2022 - Elsevier
Dupilumab, an IL-4/IL-13 receptor blocker, has been linked to emergent seronegative
inflammatory arthritis and psoriasis that form part of the spondyloarthropathy spectrum. We …

Genome-wide association analysis of psoriatic arthritis and cutaneous psoriasis reveals differences in their genetic architecture

PE Stuart, RP Nair, LC Tsoi, T Tejasvi, S Das… - The American Journal of …, 2015 - cell.com
Psoriasis vulgaris (PsV) is a common inflammatory and hyperproliferative skin disease. Up
to 30% of people with PsV eventually develop psoriatic arthritis (PsA), an inflammatory …

Overlap** features of psoriasis and atopic dermatitis: from genetics to immunopathogenesis to phenotypes

YC Tsai, TF Tsai - International Journal of Molecular Sciences, 2022 - mdpi.com
Psoriasis (PSO) and atopic dermatitis (AD) were once considered to be mutually exclusive
diseases, but gradually regarded as a spectrum of disease. Shared genetic loci of both …

Dense genoty** of immune-related susceptibility loci reveals new insights into the genetics of psoriatic arthritis

J Bowes, A Budu-Aggrey, U Huffmeier, S Uebe… - Nature …, 2015 - nature.com
Psoriatic arthritis (PsA) is a chronic inflammatory arthritis associated with psoriasis and,
despite the larger estimated heritability for PsA, the majority of genetic susceptibility loci …

Biomarkers in psoriatic arthritis: A meta-analysis and systematic review

T Wirth, N Balandraud, L Boyer, P Lafforgue… - Frontiers in …, 2022 - frontiersin.org
Introduction Psoriatic arthritis (PsA) is a chronic inflammatory disease that frequently
develops in patients with psoriasis (PsO) but can also occur spontaneously. As a result, PsA …