Pediatric ependymomas comprise biologically distinct tumor entities with different (epi)
genetics, age distribution and localization, as well as a different prognosis. Regarding risk …

Ependymal neoplasms are a heterogenous group of neoplasms arising from the progenitors
of the cells lining the ventricular system and the spinal central canal. During the last few …

Recent analyses have shown that, whereas cancer survival overall has been improving, it
has not improved for adolescents and young adults ages 15–39 years (AYA). The clinical …

The spatiotemporal regulation of cell fate specification in the human develo** spinal cord
remains largely unknown. In this study, by performing integrated analysis of single-cell and …

Brain tumors are the most common solid tumors in children and are associated with high
mortality. The most common childhood brain tumors are grouped as low-grade gliomas …

Ependymomas are rare glial tumors with clinical and biological heterogeneity, categorized
into supratentorial ependymoma, posterior fossa ependymoma, and spinal cord …

Pediatric intracranial ependymoma has seen a recent exponential expansion of biological
findings, rapidly dividing the diagnosis into several subgroups, each with specific molecular …

Study Design. This was as clinical retrospective study. Objectives. We sought to evaluate the
characteristics of Pediatric intramedullary spinal cord tumors (PISCTs) and to identify …

The fifth edition of the WHO Classification of Tumors of the Central Nervous System (CNS),
published in 2021, established new approaches to both CNS tumor nomenclature and …

The fifth edition of the World Health Organization classification of tumors of the central
nervous system (CNS), published in 2021, introduces major shifts in the classification of …