Next-generation sequencing (NGS) technology has expanded in the last decades with
significant improvements in the reliability, sequencing chemistry, pipeline analyses, data …

Advances in biomarkers, targeted therapies, and immuno-oncology have transformed the
clinical management of patients with advanced NSCLC. For oncogene-driven tumors, there …

Purpose: To analytically and clinically validate a circulating cell-free tumor DNA sequencing
test for comprehensive tumor genoty** and demonstrate its clinical feasibility …

Introduction Our aim was to update global lung cancer epidemiology and describe changing
trends and disparities. Methods We presented country-specific incidence and mortality from …

Next-generation sequencing of cell-free circulating solid tumor DNA addresses two
challenges in contemporary cancer care. First this method of massively parallel and deep …

Simple Summary Rat sarcoma virus (RAS) GTP-ase proteins represent a key element in
cellular proliferation, growth, and differentiation. Three different isoforms of RAS proteins …

Treatment for non-small-cell lung cancer is evolving from the use of cytotoxic chemotherapy
to personalised treatment based on molecular alterations. This past decade has witnessed …

PURPOSE The aim of the current study was to assess the economic impact of using next-
generation sequencing (NGS) versus single-gene testing strategies among patients with …

Purpose We report the experience with 2,000 consecutive patients with advanced cancer
who underwent testing on a genomic testing protocol, including the frequency of actionable …

Cancer with heavily economic and social burden is the hot point in the field of medical
research. Some remarkable achievements have been made; however, the exact …