Abstract Poly (α-l-lysine)(PLL) is a class of water-soluble, cationic biopolymer composed of α-
l-lysine structural units. The previous decade witnessed tremendous progress in the …

Polypeptides have attracted considerable attention in recent decades due to their inherent
biodegradability and tunable cytocompatibility. Macromolecular design in conjunction with …

The recent emergence of nanomedicine has revolutionized the therapeutic landscape and
necessitated the creation of more sophisticated drug delivery systems. Polymeric …

Reactive oxygen species (ROS) play a key role in several biological functions of living
organisms such as regulation of cell signalling, production of some hormones, modulation of …

Biological barriers hamper the efficient delivery of drugs and genes to targeted sites. Cell
penetrating peptides (CPP) have the ability to rapidly internalize across biological …

In the field of biomedicine, stimuli-responsive drug delivery systems (DDSs) have become
increasingly popular due to their site-specific release ability in response to a certain …

Nanomedicines afford unique advantages in therapeutic intervention against tumors.
However, conventional nanomedicines have failed to achieve the desired effect against …

Nanomedicines have been regarded as a potential approach in the field of cancer treatment
due to their unique advantages. Although improved therapeutic efficacy can be achieved …

Various formulations of polymeric micelles, tiny spherical structures made of polymeric
materials, are currently being investigated in preclinical and clinical settings for their …

The selective infiltration of cell membranes and tissue barriers often blocks the entry of most
active molecules. This natural defense mechanism prevents the invasion of exogenous …