Atopic dermatitis: global epidemiology and risk factors

S Nutten - Annals of nutrition and metabolism, 2015 - karger.com
Atopic dermatitis (AD) is a chronic inflammatory skin disease posing a significant burden on
health-care resources and patients' quality of life. It is a complex disease with a wide …

[HTML][HTML] The atopic march: progression from atopic dermatitis to allergic rhinitis and asthma

SK Bantz, Z Zhu, T Zheng - Journal of clinical & cellular …, 2014 - ncbi.nlm.nih.gov
The development of atopic dermatitis (AD) in infancy and subsequent allergic rhinitis and
asthma in later childhood is known as the atopic march. This progressive atopy is dependent …

The important role of stratum corneum lipids for the cutaneous barrier function

J Van Smeden, M Janssens, GS Gooris… - Biochimica et Biophysica …, 2014 - Elsevier
The skin protects the body from unwanted influences from the environment as well as
excessive water loss. The barrier function of the skin is located in the stratum corneum (SC) …

Atopic dermatitis in diverse racial and ethnic groups—variations in epidemiology, genetics, clinical presentation and treatment

BP Kaufman, E Guttman‐Yassky… - Experimental …, 2018 - Wiley Online Library
Atopic dermatitis (AD) is a chronic inflammatory skin condition that affects diverse ethnic
groups with varying prevalence. Despite a predominance of studies in individuals of …

Tight junction defects in patients with atopic dermatitis

A De Benedetto, NM Rafaels, LY McGirt… - Journal of Allergy and …, 2011 - Elsevier
BACKGROUND: Atopic dermatitis (AD) is characterized by dry skin and a hyperactive
immune response to allergens, 2 cardinal features that are caused in part by epidermal …

Epicutaneous sensitization in the development of food allergy: what is the evidence and how can this be prevented?

HA Brough, KC Nadeau, SB Sindher, SS Alkotob… - Allergy, 2020 - Wiley Online Library
There is increasing evidence regarding the importance of allergic sensitization through the
skin. In this review, we provide an overview of the atopic march and immune mechanism …

New insights into the epidemiology of childhood atopic dermatitis

C Flohr, J Mann - Allergy, 2014 - Wiley Online Library
There is a growing desire to explain the worldwide rise in the prevalence of atopic dermatitis
(AD). Trend data on the burden of AD suggest that the picture in the develo** world may …

Epidermal barrier dysfunction in atopic dermatitis

MJ Cork, S Danby, Y Vasilopoulos… - Textbook of Atopic …, 2008 - taylorfrancis.com
Atopic dermatitis (AD) is a chronic inflammatory skin disease associated with cutaneous
hyper-reactivity to environmental triggers that are innocuous to normal, non-atopic …

Stratum corneum lipids: their role for the skin barrier function in healthy subjects and atopic dermatitis patients

J Van Smeden, JA Bouwstra - Skin barrier function, 2016 - karger.com
Human skin acts as a primary barrier between the body and its environment. Crucial for this
skin barrier function is the lipid matrix in the outermost layer of the skin, the stratum corneum …

From atopic dermatitis to asthma: the atopic march

JM Spergel - Annals of allergy, asthma & immunology, 2010 - Elsevier
OBJECTIVE: To examine the mechanisms whereby allergen exposure through the
epidermis could initiate systemic allergy and predispose individuals to the development of 1 …