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[HTML][HTML] Pharmaceutical amorphous solid dispersion: A review of manufacturing strategies
Amorphous solid dispersions (ASDs) are popular for enhancing the solubility and
bioavailability of poorly water-soluble drugs. Various approaches have been employed to …
bioavailability of poorly water-soluble drugs. Various approaches have been employed to …
Advancement in solubilization approaches: A step towards bioavailability enhancement of poorly soluble drugs
A drug's aqueous solubility is defined as the ability to dissolve in a particular solvent, and it
is currently a major hurdle in bringing new drug molecules to the market. According to some …
is currently a major hurdle in bringing new drug molecules to the market. According to some …
Overview of nanoparticulate strategies for solubility enhancement of poorly soluble drugs
Poor aqueous solubility and poor bioavailability are major issues with many pharmaceutical
industries. By some estimation, 70–90% drug candidates in development stage while up-to …
industries. By some estimation, 70–90% drug candidates in development stage while up-to …
Nanocurcumin: a promising candidate for therapeutic applications
Curcuma longa is an important medicinal plant and a spice in Asia. Curcumin
(diferuloylmethane) is a hydrophobic bioactive ingredient found in a rhizome of the C. longa …
(diferuloylmethane) is a hydrophobic bioactive ingredient found in a rhizome of the C. longa …
Electrospun amorphous solid dispersions of poorly water-soluble drugs: A review
The development of oral dosage forms for poorly water-soluble active pharmaceutical
ingredients (APIs) is a persistent challenge. A range of methods has been explored to …
ingredients (APIs) is a persistent challenge. A range of methods has been explored to …
Amorphous solid dispersions: Rational selection of a manufacturing process
Amorphous products and particularly amorphous solid dispersions are currently one of the
most exciting areas in the pharmaceutical field. This approach presents huge potential and …
most exciting areas in the pharmaceutical field. This approach presents huge potential and …
Current trends on solid dispersions: past, present, and future
Solid dispersions have achieved significant interest as an effective means of enhancing the
dissolution rate and thus the bioavailability of a range of weakly water‐soluble drugs. Solid …
dissolution rate and thus the bioavailability of a range of weakly water‐soluble drugs. Solid …
Enhancing curcumin oral bioavailability through nanoformulations
Curcumin is a promising therapeutic agent that exhibits manifold therapeutic activities.
However, it is challenging to study curcumin as it exhibits poor aqueous solubility and low …
However, it is challenging to study curcumin as it exhibits poor aqueous solubility and low …
Nanocurcumin: a promising therapeutic advancement over native curcumin
Curcumin, a naturally occurring polyphenolic compound, is known to have a wide range of
therapeutic and pharmacological properties. Although it is a considerably promising …
therapeutic and pharmacological properties. Although it is a considerably promising …
[HTML][HTML] Revealing facts behind spray dried solid dispersion technology used for solubility enhancement
Poor solubility and bioavailability of an existing or newly synthesized drug always pose
challenge in the development of efficient pharmaceutical formulation. Numerous …
challenge in the development of efficient pharmaceutical formulation. Numerous …