Ionizing radiation biomarkers in epidemiological studies–an update

J Hall, PA Jeggo, C West, M Gomolka… - … Research/Reviews in …, 2017 - Elsevier
Recent epidemiology studies highlighted the detrimental health effects of exposure to low
dose and low dose rate ionizing radiation (IR): nuclear industry workers studies have shown …

A review of radiation-induced alterations of multi-omic profiles, radiation injury biomarkers, and countermeasures

SK Shakyawar, NK Mishra… - Radiation …, 2023 - meridian.allenpress.com
Increasing utilization of nuclear power enhances the risks associated with industrial
accidents, occupational hazards, and the threat of nuclear terrorism. Exposure to ionizing …

Ferredoxin reductase is critical for p53-dependent tumor suppression via iron regulatory protein 2

Y Zhang, Y Qian, J Zhang, W Yan, YS Jung… - Genes & …, 2017 - genesdev.cshlp.org
Ferredoxin reductase (FDXR), a target of p53, modulates p53-dependent apoptosis and is
necessary for steroidogenesis and biogenesis of iron–sulfur clusters. To determine the …

FDXR is a biomarker of radiation exposure in vivo

G O'Brien, L Cruz-Garcia, M Majewski, J Grepl… - Scientific reports, 2018 - nature.com
Previous investigations in gene expression changes in blood after radiation exposure have
highlighted its potential to provide biomarkers of exposure. Here, FDXR transcriptional …

RENEB Inter-laboratory comparison 2021: Inter-assay comparison of eight dosimetry assays

M Port, JF Barquinero, D Endesfelder… - Radiation …, 2023 - meridian.allenpress.com
Tools for radiation exposure reconstruction are required to support the medical management
of radiation victims in radiological or nuclear incidents. Different biological and physical …

Inter-laboratory comparison of gene expression biodosimetry for protracted radiation exposures as part of the RENEB and EURADOS WG10 2019 exercise

M Abend, SA Amundson, C Badie, K Brzoska… - Scientific reports, 2021 - nature.com
Large-scale radiation emergency scenarios involving protracted low dose rate radiation
exposure (eg a hidden radioactive source in a train) necessitate the development of high …

[HTML][HTML] RENEB inter-laboratory comparison 2021: the gene expression assay

M Abend, SA Amundson, C Badie… - Radiation …, 2023 - meridian.allenpress.com
Early and high-throughput individual dose estimates are essential following large-scale
radiation exposure events. In the context of the Running the European Network for …

Early molecular markers for retrospective biodosimetry and prediction of acute health effects

M Abend, WF Blakely, P Ostheim… - Journal of …, 2022 - iopscience.iop.org
Radiation-induced biological changes occurring within hours and days after irradiation can
be potentially used for either exposure reconstruction (retrospective dosimetry) or the …

Transcriptomics for radiation biodosimetry: progress and challenges

SA Amundson - International journal of radiation biology, 2023 - Taylor & Francis
Purpose Transcriptomic-based approaches are being developed to meet the needs for large-
scale radiation dose and injury assessment and provide population triage following a …

Integrating evolutionarily conserved mechanism of response to radiation for exploring novel Caenorhabditis elegans radiation-responsive genes for estimation of …

L Zhao, Z Li, B Huang, D Mi, D Xu, Y Sun - Chemosphere, 2024 - Elsevier
During space exploration, space radiation is widely recognized as an inescapable perilous
stressor, owing to its capacity to induce genomic DNA damage and escalate the likelihood of …