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[HTML][HTML] Overview of the manufacturing methods of solid dispersion technology for improving the solubility of poorly water-soluble drugs and application to anticancer …
P Tran, YC Pyo, DH Kim, SE Lee, JK Kim, JS Park - Pharmaceutics, 2019 - mdpi.com
Approximately 40% of new chemical entities (NCEs), including anticancer drugs, have been
reported as poorly water-soluble compounds. Anticancer drugs are classified into biologic …
reported as poorly water-soluble compounds. Anticancer drugs are classified into biologic …
Pharmaceutical dispersion techniques for dissolution and bioavailability enhancement of poorly water-soluble drugs
X Zhang, H **ng, Y Zhao, Z Ma - Pharmaceutics, 2018 - mdpi.com
Over the past decades, a large number of drugs as well as drug candidates with poor
dissolution characteristics have been witnessed, which invokes great interest in enabling …
dissolution characteristics have been witnessed, which invokes great interest in enabling …
Cilostazol-loaded solid lipid nanoparticles: Bioavailability and safety evaluation in an animal model
Cilostazol (CLZ) is an antiplatelet agent with limited solubility (∼ 6 μg/ml at 25° C), poor
absorption and low oral bioavailability. In this study, solid lipid nanoparticles (SLNs) were …
absorption and low oral bioavailability. In this study, solid lipid nanoparticles (SLNs) were …
[PDF][PDF] RETRACTED ARTICLE: Potential of solid dispersions to enhance solubility, bioavailability, and therapeutic efficacy of poorly water-soluble drugs: newer …
Abstract We, the Editors and Publisher of Drug Delivery have retracted the following article:
Sultan Alshehri, Syed Sarim Imam, Afzal Hussain, Mohammad A. Altamimi, Nabil K …
Sultan Alshehri, Syed Sarim Imam, Afzal Hussain, Mohammad A. Altamimi, Nabil K …
Development, Characterization, and Evaluation of SLN‐Loaded Thermoresponsive Hydrogel System of Topotecan as Biological Macromolecule for Colorectal …
Background. Chemotherapeutic drugs cause severe toxicities if administered unprotected,
without proper targeting, and controlled release. In this study, we developed topotecan‐(TPT …
without proper targeting, and controlled release. In this study, we developed topotecan‐(TPT …
Proniosomes derived niosomes: recent advancements in drug delivery and targeting
Vesicular drug delivery systems have gained wide attention in the field of nanotechnology.
Among them proniosomes become the superior over other vesicular carriers. Proniosomes …
Among them proniosomes become the superior over other vesicular carriers. Proniosomes …
Nose to brain delivery of escitalopram-loaded nano-structured lipid carriers thermosensitive gel: Formulation, physiochemical, pharmacokinetic and …
The primary focus of the undertaken research was to design and develop poloxamer-based
thermosensitive gel system of escitalopram-loaded nano-structured lipid carriers (ESC …
thermosensitive gel system of escitalopram-loaded nano-structured lipid carriers (ESC …
Levosulpiride-loaded nanostructured lipid carriers for brain delivery with antipsychotic and antidepressant effects
Aims Herein, we investigate the potential of levosulpiride-loaded nanostructured lipid
carriers (LEVO-NLCs) for effective brain delivery with anti-psychotic and antidepressant …
carriers (LEVO-NLCs) for effective brain delivery with anti-psychotic and antidepressant …
[HTML][HTML] Self-emulsifying drug delivery systems (SEDDS): measuring energy dynamics to determine thermodynamic and kinetic stability
This research was designed to identify thermodynamically and kinetically stable lipidic self-
emulsifying formulations through simple energy dynamics in addition to highlighting and …
emulsifying formulations through simple energy dynamics in addition to highlighting and …
Development, in-vitro and in-vivo evaluation of ezetimibe-loaded solid lipid nanoparticles and their comparison with marketed product
This study aims to develop ezetimibe-loaded solid lipid nanoparticles (SLNs) and compare
them with marketed product and drug suspension for dissolution and bioavailability …
them with marketed product and drug suspension for dissolution and bioavailability …