Autophagy in ovary and polycystic ovary syndrome: role, dispute and future perspective

S Kumariya, V Ubba, RK Jha, JR Gayen - Autophagy, 2021 - Taylor & Francis
Polycystic ovary syndrome (PCOS) is a unification of endocrine and metabolic disorders and
has become immensely prevalent among women of fertile age. The prime organ affected in …

Cell origins of high-grade serous ovarian cancer

J Kim, EY Park, O Kim, JM Schilder, DM Coffey… - Cancers, 2018 - mdpi.com
High-grade serous ovarian cancer, also known as high-grade serous carcinoma (HGSC), is
the most common and deadliest type of ovarian cancer. HGSC appears to arise from the …

Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair

FR Day, KS Ruth, DJ Thompson, KL Lunetta… - Nature …, 2015 - nature.com
Menopause timing has a substantial impact on infertility and risk of disease, including breast
cancer, but the underlying mechanisms are poorly understood. We report a dual strategy …

[HTML][HTML] In vitro growth and maturation of primordial follicles and immature oocytes

EE Telfer, CY Andersen - Fertility and sterility, 2021 - Elsevier
Cryopreservation of ovarian tissue to preserve the fertility of girls and young women at high
risk of sterility is now widely practiced. Pieces of cryopreserved ovarian cortex can be …

Role of mitochondria in the oxidative stress induced by electromagnetic fields: focus on reproductive systems

SJ Santini, V Cordone, S Falone, M Mijit… - Oxidative Medicine …, 2018 - Wiley Online Library
Modern technologies relying on wireless communication systems have brought increasing
levels of electromagnetic field (EMF) exposure. This increased research interest in the …

Understanding follicle growth in vivo

O Oktem, B Urman - Human reproduction, 2010 - academic.oup.com
Ovarian reserve is determined by the number of primordial follicles in the ovary. Quiescent
primordial follicles are activated for growth and pass through stages of development before …

Ovarian aging in humans: potential strategies for extending reproductive lifespan

MB Cavalcante, OGM Sampaio, FEA Câmara… - Geroscience, 2023 - Springer
Ovarian reserve is a term used to estimate the total number of immature follicles present in
the ovaries. Between birth and menopause, there is a progressive decrease in the number …

A review on biomaterials for ovarian tissue engineering

A Dadashzadeh, S Moghassemi, A Shavandi… - Acta biomaterialia, 2021 - Elsevier
Considerable challenges in engineering the female reproductive tissue are the follicle's
unique architecture, the need to recapitulate the extracellular matrix, and tissue …

The use of autologous platelet-rich plasma (PRP) versus no intervention in women with low ovarian reserve undergoing fertility treatment: a non-randomized …

P Melo, C Navarro, C Jones, K Coward… - Journal of assisted …, 2020 - Springer
Purpose To investigate the impact of a 3-month course of intracortical injections of
autologous platelet-rich plasma (PRP) upon ovarian reserve markers versus no intervention …

Oocyte aging: the role of cellular and environmental factors and impact on female fertility

TA Ahmed, SM Ahmed, Z El-Gammal… - Cell Biology and …, 2020 - Springer
Female aging is one of the most important factors that impacts human reproduction. With
aging, there is a natural decline in female fertility. The decrease in fertility is slow and steady …