Brain development in humans is achieved through precise spatiotemporal genetic control,
the mechanisms of which remain largely elusive. Recently, integration of technological …

Compared with traditional de novo drug discovery, drug repurposing has become an
attractive drug discovery strategy due to its low-cost and high efficiency. Through a …

Neurological complications are common in patients with COVID-19. Although severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), the causal pathogen of COVID-19, has …

The cerebral cortex constitutes more than half the volume of the human brain and is
presumed to be responsible for the neuronal computations underlying complex phenomena …

Understanding the development and dysfunction of the human brain is a major goal of
neurobiology. Much of our current understanding of human brain development has been …

Zika virus (ZIKV) is an emerging virus from the Flaviviridae family that is transmitted to
humans by mosquito vectors and represents an important health problem. Infections in …

Antimicrobial resistance continues to be a public threat on a global scale. The ongoing need
to develop new antimicrobial drugs that are effective against multi-drug-resistant pathogens …

Cerebral organoids, three-dimensional cultures that model organogenesis, provide a new
platform to investigate human brain development. High cost, variability, and tissue …

Zika Virus and Birth Defects — Reviewing the Evidence for Causality | New England Journal of
Medicine Skip to main content The New England Journal of Medicine homepage Advanced …

The epidemic history of Zika virus began in 2007, with its emergence in Yap Island in the
western Pacific, followed in 2013–14 by a larger epidemic in French Polynesia, south …