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Review on potential biological activities of thiosemicarbazides
Heterocycles have contributed to the development of society from a biological and industrial
point of view as well as to improve the quality of life. During the past few decades, interest …
point of view as well as to improve the quality of life. During the past few decades, interest …
Transalkylidation reaction: Green, catalyst-free synthesis of thiosemicarbazones and solving the NMR conflict between their acyclic structure and intramolecular …
ABSTRACT A series of arylidene thiosemicarbazides have been prepared by a new method,
which was titled as transalkylidation. This method is an effective, fast, green and clean …
which was titled as transalkylidation. This method is an effective, fast, green and clean …
Exploring molecular structure, spectral features, electronic properties and molecular docking of a novel biologically active heterocyclic compound 4 …
R Arivazhagan, C Sridevi, A Prakasam - Journal of Molecular Structure, 2021 - Elsevier
The experimental and theoretical studies on the structure and vibrations of 4-phenyl
thiosemicarbazide (PTSC)(IUPAC: 3-amino-1-phenylthiourea) have been carried out using …
thiosemicarbazide (PTSC)(IUPAC: 3-amino-1-phenylthiourea) have been carried out using …
[HTML][HTML] Synthesis and anthelmintic activity of new thiosemicarbazide derivatives—A preliminary study
K Dziduch, P Kołodziej, A Paneth, A Bogucka-Kocka… - Molecules, 2020 - mdpi.com
Parasitic infections caused by different species of intestinal helminths still poses a threat to
public health. There is a need to search for new, effective anthelmintic drugs. A series of …
public health. There is a need to search for new, effective anthelmintic drugs. A series of …
Studies on isoniazid derivatives through a medicinal chemistry approach for the identification of new inhibitors of urease and inflammatory markers
A library of thiosemicarbazide derivatives of isoniazid 3–27, was synthesized and evaluated
for their anti-inflammatory and urease inhibition activities, by using in vitro bioassays. Among …
for their anti-inflammatory and urease inhibition activities, by using in vitro bioassays. Among …
Novel thiosemicarbazide–oxadiazole hybrids as unprecedented inhibitors of yeast α-glucosidase and in silico binding analysis
Compounds 1–18, new oxadiazole–thiosemicarbazide hybrids, were synthesized using a
five-step reaction sequence in excellent yields. All the synthesized analogs exhibited …
five-step reaction sequence in excellent yields. All the synthesized analogs exhibited …
[HTML][HTML] Supramolecular aggregation of lead (II) perchlorate and a thiosemicarbazide derivative linked by a myriad of non-covalent interactions
In this work, we report on a new lead (II) coordination complex [Pb 2 L 2 (CH 3 CN)(ClO 4)
2]· 2H 2 O (1· 2H 2 O), which was readily synthesized from a mixture of Pb (ClO 4) 2· 3H 2 O …
2]· 2H 2 O (1· 2H 2 O), which was readily synthesized from a mixture of Pb (ClO 4) 2· 3H 2 O …
Ultrasonic-assisted synthesis of amantadine derivatives-in vitro urease and α-glucosidase inhibitory activities, mechanistic, and computational studies
Ultrasonic synthesis of 26 amantadine derivatives,(3-28) including seven new compounds,
are reported with significantly reduced synthesis time and increased percentage yield …
are reported with significantly reduced synthesis time and increased percentage yield …
Rationally designed hecogenin thiosemicarbazone analogs as novel MEK inhibitors for the control of breast malignancies
Natural products have documented oncology success history as valuable scaffolds for
selective target modulation. Herein, the sapogenin hecogenin (1) was screened for its anti …
selective target modulation. Herein, the sapogenin hecogenin (1) was screened for its anti …
New Thiosemicarbazide Derivatives with Multidirectional Biological Action
P Lasek, U Kosikowska, P Kołodziej… - Molecules, 2024 - mdpi.com
Over the years, several new medicinal substances have been introduced for the treatment of
diseases caused by bacteria and parasites. Unfortunately, due to the production of …
diseases caused by bacteria and parasites. Unfortunately, due to the production of …