Cancer is a severe disease that results in death in all countries of the world. A nano-based
drug delivery approach is the best alternative, directly targeting cancer tumor cells with …

Sonochemistry is the use of ultrasonic waves in an aqueous medium, to generate acoustic
cavitation. In this context, sonochemistry emerged as a focal point over the past few …

In this study, a seamless scale-up strategy for the antisolvent precipitation process was
developed using a series of ultrasonic microreactors (USMRs). The key principle of this …

In vitro transcription (IVT) is the main manufacturing method to produce mRNA vaccines. In
this study, a fed-batch strategy was systematically optimized for IVT process with dual goals …

In the spotlight of successful breakthrough of the COVID-19 mRNA vaccines, lipid
nanoparticles are becoming an important vehicle to deliver a variety of therapeutics. The …

Microfluidic technology facilitates precise control over fluid mixing and interactions between
the components, including self-assembly and precipitation. It offers new options for …

Microreactors are essential tools for the production of lipid nanoparticles (LNPs), offering
precise control over particle size and monodispersity. However, the effect of microchannel …

Ultrasonic-assisted supercritical fluid separation (USFS) was firstly applied to regulate
solubility and remove plasticizers from ganoderma lucidum spores' oil to improve product …

Microfluidics have been widely used for the preparation of small and monodisperse
liposomes but it still suffered from the challenges with fouling-free, velocity independent and …

Liposomes are widely utilized in therapeutic nanosystems as promising drug carriers for
cancer treatment, which requires a meticulous synthesis approach to control the …