The purpose of this review is to explore self-organizing mechanisms that pattern
microtubules (MTs) and spatially organize animal cell cytoplasm, inspired by recent …

The mitotic spindle performs the universal and crucial function of segregating chromosomes
to daughter cells, and all spindles share common characteristics that facilitate this task. The …

Proliferation of Plasmodium falciparum in red blood cells is the cause of malaria and is
underpinned by an unconventional cell division mode, called schizogony. Contrary to model …

Background Current models of cell-cycle control, based on classic studies of fused cells,
predict that nuclei in a shared cytoplasm respond to the same CDK activities to undergo …

Nuclear movement within a cell occurs in a variety of eukaryotic organisms including yeasts
and filamentous fungi. Fungal molecular genetic studies identified the minus-end-directed …

Ploidy variation is found in contexts as diverse as solid tumors, drug resistance in fungal
infection, and normal development. Altering chromosome or genome copy number supports …

Multinucleated cells are important in many organisms, but the mechanisms governing the
movements of nuclei sharing a common cytoplasm are not understood. In the hyphae of the …

Augmin is a protein complex that binds to spindle microtubules (MTs), recruits the potent MT
nucleator, γ-tubulin, and thereby promotes the centrosome-independent MT generation …

Interactions between actins and microtubules play an important role in many fundamental
cellular processes in eukaryotes. Although several studies have shown actins and …

Rapid proliferation of Plasmodium falciparum parasites in human red blood cells is the
cause of malaria and is underpinned by an unconventional cell division mode, called …